Octreotide (SMS), a somatostatin analogue, is an established antigrowth peptide, but it does not effectively inhibit the growth of insulinoma cells. In order to study the mechanisms that underlie this apparent lack of an antiproliferative effect on insulinoma tumor cells we established the rat insulinoma cell line, RINm5F, in culture. Cells in culture were tested by incubation in media with and...

BACKGROUND Self-management support is considered to be an essential part of diabetes care. However, the implementation of self-management support within healthcare settings has appeared to be challenging and there is increased interest in "real world" best practice examples to guide policy efforts. In order to explore how different approaches to diabetes care and differences in management struc...

Smith-Magenis syndrome (SMS) is a rare syndrome with multiple congenital malformations, including development and mental retardation, behavioral problems and a distinct facial appearance. SMS is caused by haploinsufficiency of RAI1 (deletion or mutation of RAI1). We describe an eight-year-old female Chinese patient with multiple malformations, congenital heart defect, mental retardation, ...

A new manufacturing system, Seru Manufacturing Systems(SMS), has been widely applied in Japanese electronic industry. Through comparing with other three similar manufacturing systems, the organizational characeristics of SMS were discussed from three levels based on case studies, i.e., manufacturing system, manufacturing strategy, and industry application. The results show that SMS can satisfy ...

OBJECTIVES To explore feedback on tailored SMS reminders to encourage medication adherence and outpatient treatment among patients taking antipsychotic medication, and associations related to the feedback. DESIGN A cross-sectional survey nested within a nationwide randomised clinical trial ("Mobile.Net" ISRCTN27704027). SETTING Psychiatric outpatient care in Finland. PARTICIPANTS Between ...

BACKGROUND Turnaround time (TAT) is an important indicator of laboratory performance. It is often difficult to achieve fast TAT for blood tests conducted at clinics in developing countries. This is because clinics where the patient is treated are often far away from the laboratory, and transporting blood samples and test results between the two locations creates significant delay. Recent effort...

The Scalable Modeling System (SMS) is a directive-based parallelization tool. The user inserts directives in the form of comments into existing Fortran code. SMS translates the code and directives into a parallel version that runs on shared and distributed memory high-performance computing platforms. Directives are available to support array re-sizing, inter-process communications, loop transla...

Cellular and tissue injury associated with reactive oxygen species (ROS) has been reported in many kinds of disorders. While the antioxidant enzymes play critical roles in inhibiting the ROS-mediated injury, glutathione peroxidase (GPx) is scavenging hydroperoxides including H(2)O(2). We previously reported that Shengmai-san (SMS), a traditional Chinese medicine, prevented ischemia/reperfusion ...

OBJECTIVE To understand how a pilot intervention combining SMS reminders with real-time adherence monitoring improved adherence to HIV antiretroviral therapy (ART) for adults initiating treatment in rural Uganda. DESIGN Qualitative study, conducted with a pilot randomized controlled trial. METHODS Sixty-two pilot intervention study participants took part in qualitative interviews on: prefer...