OBJECTIVES Aneurysmal subarachnoid hemorrhage often leads to death and poor clinical outcome. Injury occurring during the first 72 hours is termed "early brain injury," with disruption of the nitric oxide pathway playing an important pathophysiologic role in its development. Quantitative electroencephalographic variables, such as α/δ frequency ratio, are surrogate markers of cerebral ischemia. ...

Background: Many common cancers, such as prostate, breast, and colon, are caused by harmful substances and compounds contained in processed foods, including nitrite-treated meats. The aim of this study was to investigate the possibility of replacing sodium nitrite with Monascus purpureus pigment in sausage and to assess its antimicrobial, antioxidant, color, and sensory properties. Methods: The...

We report a case of fatal methaemoglobinaema resulting from sodium nitrite poisoning. A 28 year old woman arrested in the emergency department following collapse. During resuscitation venous blood gas revealed methaemoglobin percentage 81%. Following treatment with methylene blue, bicarbonate and adrenaline, decreased. Prior to transfer intensive care, CT head extensive hypoxic brain injury. Tw...

Although sodium nitroprusside (SNP) is often used in pediatric intensive care units, cyanide toxicity can occur after SNP treatment. To treat SNP-induced cyanide poisoning, antidotes such as amyl nitrite, sodium nitrite, sodium thiosulfate, and hydroxycobalamin should be administered immediately after diagnosis. Here, we report the first case of a very young infant whose SNP-induced cyanide poi...

iii CHAPTER 1. GENERAL INTRODUCTION 1 Thesis Organization 2 CHAPTER 2. LITERATURE REVIEW 3 I. Conventional Curing 3 a. Salt 3 b. Phosphate 4 c. Sodium Lactate 6 d. Nitrate and Nitrite 7 e. Reductants 11 II. Natural Curing 13 a. Celery Powder 14 b. Sea Salt 15 c. Starter Cultures 16 d. Cherry Powder 17 e. Lemon Powder 18 f. Raw Sugar 19 g. Natural and Organic Markets 20 References 23 CHAPTER 3. ...

Liver ischemia-reperfusion injury is a major cause of primary graft non-function or initial function failure post-transplantation. In this study, we examined the effects of sodium nitrite supplementation on liver IRI in either Lactated Ringer's (LR) solution or University of Wisconsin (UW) solution. The syngeneic recipients of liver grafts were also treated with or without nitrite by intra-peri...