The binding of drugs by plasma proteins is an important phenomenon, because it influences the size of the free fraction of the drugs in plasma. In this study the influence of dipyridamole (DP) on the protein binding of propranolol (PL) and PL on the protein binding of DP were studied alone and in the presence of nicotine (NC).        The equilibrium dialysis was employed for protein bin...

The title compound, C(51)H(78)INO(12), contains a 29-membered ring incorporating amide, lactone and ester groups. It contains a total of 15 stereogenic centres. In the crystal, mol-ecules are linked by O-H⋯O hydrogen bonds, forming C(8) chains propagating in [100]. A weak intra-molecular O-H⋯O inter-action also occurs.

(40)Ar/(39)Ar dates of emplacement-related metamorphic rocks beneath the Samail ophiolite in Oman show that cooling to <525 degrees C occurred within approximately 1 million years of igneous crystallization of the ophiolite. This unexpectedly short time span and rapid cooling means that old, cold continental or oceanic lithosphere must have been adjacent to the ophiolite during spreading and th...

The National Aeronautics and Space Administration Space (NASA) Shuttle program is a multi-billion dollar activity scheduled to span over 40 years. Maintaining such software with requirements for high reliability and mission safety taxes current development methods. In this paper we present how Independent Verification and Validation (IV&V) activities have evolved in order to provide for these r...

This is the case report of a 58-year-old living man with uncomplicated congenital corrected transposition of the great vessels proved by cardiac catheterization and selective cineangiocardiography. Only six patients (3 percent) have lived beyond the age of 40 years despite the theoretic speculation of a normal life span. Selective coronary ateriograms revealed that the left coronary artery supp...

We have examined the proliferative behavior in culture of stromal cells of fibroblast morphology taken from various stages in the development of experimentally induced epithelial tumors in the rat thyroid. In this model long-term stimulation by an elevated level of serum thyroid stimulating hormone leads first to hyperplasia, then to multiple benign, and finally malignant tumors. Fibroblasts fr...

Growth hormone receptor knockout (GHRKO) mice live about 40%-55% longer than their normal (N) littermates. Previous studies of 21-month-old GHRKO and N mice showed major alterations of the hepatic expression of genes involved in insulin signaling. Differences detected at this age may have been caused by the knockout of the growth hormone receptor (GHR) or by differences in biological age betwee...

how to cite this article: khosravi fard e, keelor jl, akbarzadeh bagheban ar, keith rw. comparison of the ravlt and digit test with typically achieving and gifted students. iran j child neurol. spring 2016; 10(2):26-37. abstract objective in this study, different kinds of memory were evaluated using rey auditory verbal learning (ravlt) test and were compared between two groups of typical and gi...

However, the 21 days that the chick spends in the incubator is significant proportion of its life; for a broiler killed at 40 days, 34 % of its total life span is spent in the egg. Recent research has shown that aspects of incubation and hatchery process control can have profound effects on broiler performance all the way up to slaughter weights. Often, small changes will generate significant i...

The case of a 73-year-old white man with corrected transposition of the great vessels and associated mitral and mild aortic regurgitation is reported. The patient's survival was the longest of any patient with this defect reported to date. Although the condition is theoretically compatible with a normal life span, few patients with this lesion survive past 40 years of age because of associated ...