It is possible that there may be differences in the fundamental physical parameters from one side of the observed universe to the other. I show that the cosmological constant is likely to be the most sensitive of the physical parameters to possible spatial variation, because a small variation in any of the other parameters produces a huge variation of the cosmological constant. It therefore pro...

We present an improved microfluidic design for generating spatial and temporal gradients. The basic functional elements are bifurcated and trifurcated channels used to split flow between two and three channels, respectively. We use bifurcated channels on the exterior of the channel manifold and trifurcated channels in the interior with mixing tees to recombine flows. For N gradient-forming leve...

The mechanical response of materials with spatial gradients in composition and structure is of considerable interest in disciplines as diverse as tribology, geology, optoelectronics, biomechanics, fracture mechanics, and nanotechnology. The damage and failure resistance of surfaces to normal and sliding contact or impact can be changed substantially through such gradients. This review assesses ...

Species' geographical distributions are tracking latitudinal and elevational surface temperature gradients under global climate change. To evaluate the opportunities to track these gradients across space, we provide a first baseline assessment of the steepness of these gradients for the world's terrestrial birds. Within the breeding ranges of 9,014 bird species, we characterized the spatial gra...