OBJECTIVE Atypical antipsychotic drug treatment is clinically effective with a low risk of extrapyramidal symptoms. Explanations for the mechanism underlying this beneficial therapeutic profile of atypical over typical antipsychotic agents include 1) simultaneous antagonism of dopamine D(2) and serotonin 5-HT(2A) receptors or 2) selective action at limbic cortical dopamine D(2)-like receptors w...

68 Objective: In this study, we tried to estimate human absorbed dose of Ga-NODAGA-glycine as a new potential positron emission tomography (PET) renal agent based on the biodistribution data reported in healthy rats, and compare our estimation with the available absorbed dose data from technetium-99m-diethy99m lenetriaminepentaacetic acid ( Tc-DTPA). Subjects and Methods: The medical internal r...

To the comments of Prof. Andreas Otte to our work we reply as follows: As was mentioned by Prof. Andreas Otte, our study was the first study of regional cerebral blood flow changes in patients with internet addiction. Therefore, there was not much previous, established experience to refer to. As an exploration study, it was inevitable that there were some insufficiencies. We feel great apprecia...

Well, a lot of it. SPET/CT and indeed PET/CT have arrived, and we are witnessing the first applications. Instantaneous image fusion, accurate co-registration, and often reduced imaging times are real benefits. The world of radiotherapy planning may change forever— who knows how intensity modulated radiation therapy will change and benefit from routinely available PET/CT? Of course all of this p...

The two-day Research Conferences preceding ARVO, sponsored by Vision Research, Elsevier and ARVO, are designed to provide updates on major areas of interest to the vision research community. The goal of the fourth conference, which took place on 28–29 April 2000, was to convene a multi-disciplinary audience interested in functional brain imaging in vision. The recent technological developments ...

Prostate cancer (PC) is currently the most frequently diagnosed cancer in males and constitutes a major health issue in developed countries. On the other hand, the majority of PC cases are considered clinically not significant and certainly not lethal. These discrepancies highlight the need for the early detection of especially those cases that have aggressive features and call for early an...

The aim of this study was to compare the correlation and consistency of left ventricular ejection fraction (LVEF) obtained by ECG-gated myocardial perfusion SPET (GMPS) using the four formulas (R0-R3) in ECToolbox software and by equilibrium radionuclide ventriculography (ERNV), and determine the optimal diagnostic thresholds of the four formulas in a Chinese population. A hundred and three can...

SPIRATI(I)NS OF THE SPLEEN isave beens performed ins 140 patiemsts at Kitsgs Coutity Hospital sinsce 1949, eithetas ats aid to diagnosis or in the course of hematologic research. This repot-t. summarizes the finsdinsgs ohtamed by this technic. \Vidalm late ins the 1 Ptls c-entinry, was pn-ohably the first tc) pun(-ture the spleens for diagnosis. He obtained I)lood fot (utltltn(’ from the spleen...

Megalizzi et al.’s data showing reduction of glioblastoma cells’ motility by the experimental sigma-1 agonist 4-IBP [1] is delightful news. Since we already have several approved and marketed drugs with potent sigma-1 agonist activity we can start looking at treatment consequences of their data now. The antidepressant drug fluvoxamine is an old, generic, selective serotonin reuptake inhibitor w...

Single photon emission tomography allows the imaging of dynamic brain functioning. The use of cerebral activating procedures within the scan protocol enables investigation of the mechanisms involved in specific brain functions in health and disease. Activation studies involve the comparison of at least two data sets describing brain activity generated in conditions that differ for the specific ...