OBJECTIVE To characterize and compare the MRI morphological features of the cervical vertebral column of Great Danes with and without clinical signs of cervical spondylomyelopathy (CSM). DESIGN Prospective cohort study. ANIMALS 30 Great Danes (15 clinically normal and 15 CSM-affected). PROCEDURES All dogs underwent MRI of the cervical vertebral column (C2-3 through T1-2). Features evaluat...

BACKGROUND AND PURPOSE The criteria for selecting patients who may benefit from surgery of spinal cord compression in metastatic prostate cancer are poorly defined. We therefore studied patients operated for metastatic spinal cord compression in order to evaluate outcome of surgery and to find predictors of survival. PATIENTS AND METHODS We reviewed the records of 54 consecutive patients with...

X-linked hypophosphataemic rickets is a familial form of Vitamin D resistant rickets in which gross bony and ligamentous changes may occur. Two patients showing severe spinal disease with evidence of spinal cord compression requiring neurosurgical intervention are reported. The management of such lesions may be problematic as cord compression may be found at several levels at presentation, and ...

Introduction: Germ cell tumors account for 3.5 % of pediatric and yolk sac are the most common pure malignant germ in children. Testis ovary sites involvement children older than 2 years. Case Presentation: A 20-month-old boy with a complaint limping was described this case report. Abdominal ultrasonography showed 52 × 50 mm solid abdominal mass. pelvic computed tomography scans left paraspinal...

OBJECTIVE To evaluate the effect of expansion speed on chronic compressive spinal cord injury in the rat. METHODS Thirty-six Sprague-Dawley rats were divided into four groups: a control group, a group receiving compressor in the C5-C6 epidural space with instant compression (group 1), and two other groups receiving water-absorbing polyurethane polymer sheets with two expansion speeds, which r...

Study Design Case report and literature review. Objective Multiregional spinal stenosis (MRSS) has not been described in the English literature, although a few studies report the concept of tandem spinal stenosis. Due to the concurrent spinal stenosis occurring in three separate regions of the spine, clinical presentation of MRSS may be less distinct, and its surgical treatment priorities and c...

The spinal cord is a structure which is peculiarly prone to marked loss of function when compressed. The numerous conditions which may result in pressure upon the spinal cord and consequent loss of function include intervertebral discs, osteophytic bars, tumours, haematomas, and, of course, trauma. Arachnoid calcification is a very rare and disputed cause of spinal cord compression, but the cas...

BACKGROUND The treatment of epidural spinal cord compression due to metastatic cancer represents an important clinical challenge. The NOMS (neurologic, oncologic, mechanical, and systemic) framework facilitates the determination of the optimal combination of systemic, radiation, and surgical therapies for individual patients. Spinal stereotactic radiosurgery (SRS) is an effective and safe modal...

Epidural localization of myeloid leukaemia is rarely reported. Spinal cord compression as an initial presentation of acute myeloid leukaemia is extremely rare. This is a report of a 17-year-old black boy who presented to emergency department with neurological symptoms of spinal cord compression. Imaging modalities showed multiple soft tissue masses in the epidural space. After surgical treatmen...

We have previously shown that acrolein, a lipid peroxidation byproduct, is significantly increased following spinal cord injury in vivo, and that exposure to neuronal cells results in oxidative stress, mitochondrial dysfunction, increased membrane permeability, impaired axonal conductivity, and eventually cell death. Acrolein thus may be a key player in the pathogenesis of spinal cord injury, w...