spinal cord injury (sci) leads to a significant health problem associated with a broad range of secondary complications and disabilities. in this regard, animal models can help us to understand the pathobiology of sci and evaluate the effects of potential treatments for sci. in contusion models of sci, different devices including surgical spring-loaded clips, balloons, forceps, weights and the ...

prevalence of spinal cord injury (sci) in iran is considerable and developing a national registry is substantial. registry can be a foundation of efforts for patient care improvement, clinical research facilitation, preventative strategy formulation and policymaking for better support of patients. with respect to long-term and multiple consequents of the lesions that will have a negative impact...

the pathology of spinal cord injury (sci) comprises multiple processes characterized by extensive cell death and glial scar formation, which together limits axonal regeneration. in particular, variations in chronic demyelination of the lesion have been found to be largely independent of injury intensity, suggesting a secondary pathologic origin. this chronic demyelination results in progressive...

hereby we report a patient with thalassemia major having extradural cord compression at t3-t9 levels due to a mass of extramedullary hematopoiesis (emh) tissue, whose treatment was successful with hypertransfusion therapy alone. the patient was a 23-year-old man who had not received regular blood transfusion since two years before admission. he suffered from paraparesis with a history of progre...

in this study organotypic adult spinal cord slices were used to investigate whether caspases could participate in the apoptosis of motor neurons. the thoracic region of spinal cord was sliced using a tissue chopper and cultured in a medium for 6h. morphological and biochemical features of apoptosis were assessed by fluorescent staining and terminal deoxynucleotidyl nick end labeling (tunel) met...

the initial experience concerning the use of magnetic resonance imaging in 94 patients who had sustained chronic cord injury showed its specific advantages over traditional imaging modalities. a variety of 84 cord abnormalities were identified including myelomalacia in 47%, cord cysts in 37%, focal atrophy in 11 % and cord transection in 5%. canal stenosis was seen in twenty-five patients, elev...

introduction: worldwide, every year, many people undergo spinal cord injury which is of the worst health problems and is followed by several secondary complications. today, more than half of the world population is in danger of natural disasters such as earthquake, which is one of the causes of spinal cord injuries outbreak. earthquake in bam also caused many spinal cord injured people for whom...

Background and Aim: Acute injuries of the spine and spinal cord are causing the greatest amount of disability. They produce high cost outcomes for patients and society psychologically and economically. Knowing the epidemiology of these injuries play an important role in planning for prevention and conservative treatment. But now, we have little information about this in our country. The ai...

The spinal cord is the caudal portion of the central nervous system (CNS) that extends from the lower part of the brain stem (the medulla) to the cauda equina. It receives several types of sensory information from the joints, muscles, organs and skin and contains the motoneurons responsible for voluntary/reflex movements and for the function of the autonomic nervous system. The spinal cord is d...

BACKGROUND AND PURPOSE Diffusion-weighted imaging is a robust technique for evaluation of a variety of neurologic diseases affecting the brain, and might also have applications in the spinal cord. The purpose of this study was to determine the feasibility of obtaining in vivo diffusion-weighted images of the human spinal cord, to calculate normal apparent diffusion coefficient (ADC) values, and...