Background & Aims: Generalized anxiety disorder (GAD) can be affected by different emotional, cognitive, and natural factors. The purpose of this study was to predict GAD based on emotion regulation deficits, thought-action fusion, and behavioral inhibition. Methods: This was a correlational study. The study sample was comprised of 135 patients with GAD selected from amo...

Background: Parathyroid Hormone (PTH) is secreted by parathyroid glands and controls the level of calcium in bones and kidney. PTH is a small polypeptide with 84 amino acids, but the first 34 amino acids of which are enough for hormone biological activity and can be used in the treatment of Osteoporosis. The expression efficiency of recombinant human parathyroid hormone rhPTH (1-34) or Teripara...

objective(s): brucella spp. are facultative intracellular pathogens which can stay alive and multiply in professional and nonprofessional phagocytes. immunity against brucella melitensis involves antigen-specific cd4+ and cd8+ t-cells activation and humoral immune responses. due to negative aspects of live attenuated vaccines, much attention has been focused on finding brucella-protective antig...

bacterial expression systems provide economic and logistic advantages in manufacturing proteins for human therapeutic purposes. however, most such proteins accumulate in insoluble biologicaiiy inactive form when overexpressed in bacterial cells. this is the case while attempting to produce recombinant human granulocyte-macrophage colony stimulating factor (hgm-csf) in e. coli. in this report, d...

purpose: multiple sclerosis is a progressive neurological disease and a cause of many disabilities in individuals. set of symptoms and the chronic nature of this disease, together impair the mental state of the person and cause awidervariety of psychological symptoms worsening the disease. therefor, this study aimed to evaluate the effectiveness of cognitive therapy based on mindfulness psychol...

background: cervical spine sustains most of thevertebral column injuries, among other injuries, the disc degeneration and damage that lead to replacement of the damaged disc with cage or artificial disc. methods: the c4 to c6 vertebrae of a normal subject and a person with interbody fusion cage were 3d modelled and then analyzed using finite element method. the results of maximum stress and str...

congenital fusion of the maxilla and the mandible is a rare condition. the extent of the problem ranges from simple mucosal adhesion (synechia) to severe bony fusion (syngnathia). here we present a patient with zygomatico-mandibular fusion who was treated at neonatal and infancy periods at three different stages without tracheostomy. having had recurrence for two times, porcine grafting was per...

background: infections due to pseudomonas aeruginosa are among the leading causes of morbidity and mortality in patients who suffer from impaired immune responses and chronic diseases such as cystic fibrosis. at present, aggressive antibiotic therapy is the only choice for management of p. aeruginosa infections, but emergence of highly resistant strains necessitated the development of novel alt...

objective(s):human cytomegalovirus (hcmv) remains a major morbidity and mortality cause in immuno suppressed patients. therefore, significant effort has been made towards the development of a vaccine. in this study, the expression of the pp65 and gb fusion peptides and fc domain of mouse igg2a as a novel delivery system for selective uptake of antigens by antigen-presenting cells (apcs) in pich...