One of the most important points in a supply chain is customer-driven modeling, which reduces the bullwhip effect in the supply chain, as well as the costs of investment on the inventory and efficient transshipment of the products. Their homogeneity is reflected in the Inventory Routing Problem, which is a combination of distribution and inventory management. This paper expands the classical In...

Agrobacterium tumefaciens is a natural genetic engineer widely used to deliver DNA into various recipients, including plant, yeast and fungal cells. The bacterium can transfer single-stranded DNA molecules (T-DNAs) and bacterial virulence proteins, including VirE2. However, neither the DNA nor the protein molecules have ever been directly visualized after the delivery. In this report, we adopte...

A stochastic inventory routing problem (SIRP) is typically the combination of stochastic inventory control problems and NP-hard vehicle routing problems, which determines delivery volumes to the customers that the depot serves in each period, and vehicle routes to deliver the volumes. This paper aims to solve a large scale multi-period SIRP with split delivery (SIRPSD) where a customer’s delive...

Integrating dynamic information across the senses is crucial to survival. However, most laboratory studies have only examined sensory integration for static events. Here we demonstrate that strong crossmodal integration can also occur for an emergent attribute of dynamic arrays, specifically the direction of apparent motion. The results of the present study show that the perceived direction of ...

We present a case study in the use of performance modeling for parallel application development, with a biological cell simulation as our target application. We show that a simple performance model is adequate for determining data layout for arrays and linked structures, and validate our model against experimental results for some application kernels. We quantify the importance of optimizing ac...

It was proposed that split-brain monkeys are able to perform ipsilateral eyehand response because the seeing hemisphere can cross-cue the blind hemisphere, which is in major motor control of the arm, by orienting toward a point in space and, thereby, allow for the bilateral registration of head, neck, and eye position. In the present study, accuracy of ipsilateral eye-hand response was measured...

A metric d on a finite set X is called a Kalmanson metric if there exists a circular ordering of points of X , such that d(y; u) + d(z; v) > d(y; z) + d(u; v) for all crossing pairs yu and zv of . We prove that any Kalmanson metric d is an l1-metric, i.e. d can be written as a nonnegative linear combination of split metrics. The splits in the decomposition of d can be selected to form a circula...