Thalidomide is an effective drug for the treatment of ankylosing spondylitis but might induce peripheral neuropathy. This major adverse reaction has attracted much concern. The current study aimed to observe the incidence of thalidomide-induced peripheral neuropathy among ankylosing spondylitis patients for 1 year after treatment. In this study, 207 ankylosing spondylitis cases received thalido...

STUDY DESIGN Observational analytic design with a cross-sectional approach. PURPOSE To analyze the suitability of magnetic resonance imaging (MRI) in distinguishing radiology images with a corresponding delineation of spondylitis and vertebral metastasis confirmed by histology results. OVERVIEW OF LITERATURE MRI is an accurate modality for assessing vertebrae and their disorders. Infections...

OBJECTIVES To compare the impact of ankylosing spondylitis (AS) on health-related quality of life (HRQL) and of adalimumab on initial and sustained improvement in HRQL for patients with active AS versus the general US population. METHODS Data from the 5-year ATLAS trial were analysed. HRQL burden of AS and treatment impact on HRQL were assessed by comparing health status and utility scores fr...

While it seems clear that anti-TNF treatments do improve the clinical condition of patients with ankylosing spondylitis, there is some evidence that doses much smaller than those formally studied in controlled trials may also be very effective, and we would recommend that this aspect be pursued given the overall costs involved.

[1] In the article, “The treatment strategies for spine fractures in patients with ankylosing spondylitis: A case report”, which appeared in Volume 96, Issue 44 of Medicine, affiliation a should appear as Department of Spine Surgery, Tianjin Union Medical Center. The authors would like it noted that RuSen Zhu and WenYe Song contributed equally to the article and are co-first authors. The author...

Ankylosing spondylitis, formerly known as Bechterew’s disease or MarieStrümpell disease, is a type of inflammatory rheumatic disease which affects mostly the spine. In the end-stage of this disease, patients suffer from complete fusion and rigidity of the spine—the so-called "bamboo spine". Here, you will find all the relevant facts on ankylosing spondylitis (AS) that you need for your rheumato...

Volume 43, no. 3 Spondylitis? Differently with or without Concomitant Methotrexate from Patients without Do Biologic-treated Psoriatic Arthritis Patients with Spondylitis Respond PHILIP J. MEASE http://www.jrheum.org/content/43/3/471 J Rheumatol 2016;43;471-473 http://www.jrheum.org/alerts 1. Sign up for TOCs and other alerts http://jrheum.com/faq 2. Information on Subscriptions http://jrheum...

 Background: One of the important sites for extrapulmonary TB involvement is the skeleton. Tuberculous spondylitis (Pott’s disease) comprises 50-70% of the skeletal tuberculosis. Methods: In this case series study, we prospectively investigated the result of anterior surgery alone (anterior debridement, fusion and instrumentation) in the patients with spinal tuberculosis. The patients with imma...