TROUSSOV, A., DAŘENA, F., ŽIŽKA, J., PARRA, D., BRUSILOVSKY, P.: Vectorised Spreading Activation algorithm for centrality measurement. Acta univ. agric. et silvic. Mendel. Brun., 2011, LIX, No. 7, pp. 469– 476 Spreading Activation is a family of graph-based algorithms widely used in areas such as information retrieval, epidemic models, and recommender systems. In this paper we introduce a novel...

due to its critical impact and significant destructive nature during and after seismic events, soil liquefaction and liquefactioninduced lateral ground spreading have been increasingly important topics in the geotechnical earthquake engineering field during the past four decades. the aim of this research is to develop an empirical model for the assessment of liquefaction-induced lateral ground ...

Rho guanosine triphosphatases (GTPases) are critical regulators of cytoskeletal dynamics and control complex functions such as cell adhesion, spreading, migration, and cell division. It is generally accepted that localized GTPase activation is required for the proper initiation of downstream signaling events, although the molecular mechanisms that control targeting of Rho GTPases are unknown. I...

relationships J. Chu-Carroll E. W. Brown A. Lally J. W. Murdock Answering natural-language questions may often involve identifying hidden associations and implicit relationships. In some cases, an explicit question is asked by the user to discover some hidden concept related to a set of entities. Answering the explicit question and identifying the implicit entity both require the system to disc...

We have reconstituted the platelet glycoprotein (GP) Ib-IX-mediated activation of the integrin alpha(IIb)beta(3) in a recombinant DNA expression model, and show that 14-3-3 is important in GPIb-IX signaling. CHO cells expressing alpha(IIb)beta(3) adhere poorly to vWF. Cells expressing GPIb-IX adhere to vWF in the presence of botrocetin but spread poorly. Cells coexpressing integrin alpha(IIb)be...

Ontologies and spreading activation are known terms within the scope of information retrieval. In this paper we introduce SPREADR, an integrated adaptation mechanism for web applications that uses ontologies for representing the application domain as well as context information like location, user history and local time. Those context factors can be modeled in an ontology and be linked to certa...

OBJECTIVE Integrins mediate platelet adhesion and transmit outside-in signals leading to platelet spreading. Phosphoinositide 3-kinases (PI3Ks) play a critical role in outside-in signaling and platelet spreading; however, the mechanisms of PI3K activation and function in outside-in signaling are unclear. We sought to determine the role of the Akt family of serine/threonine kinases and activatio...

This essay proposes a combination of commonsense knowledge and the spreading activation theory to strengthen the breadth of spreading activation of user’s behavioral information in the field of intelligent environment design. The ontology cited in traditional artificial intelligence is roughly used to express and share knowledge. It is described with concepts, the properties of concepts, and th...

Adhesion to ECM is required for many cell functions including cytoskeletal organization, migration, and proliferation. We observed that when cells first adhere to extracellular matrix, they spread rapidly by extending filopodia-like projections and lamellipodia. These structures are similar to the Rac- and Cdc42-dependent structures observed in growth factor-stimulated cells. We therefore inves...