Tyrosyl radicals (Y·s) are prevalent in biological catalysis and are formed under physiological conditions by the coupled loss of both a proton and an electron. Fluorotyrosines (F(n)Ys, n = 1-4) are promising tools for studying the mechanism of Y· formation and reactivity, as their pK(a) values and peak potentials span four units and 300 mV, respectively, between pH 6 and 10. In this manuscript...

BACKGROUND Two meningococcal serogroup B vaccines contain Factor H binding protein (FHbp). Binding of Factor H (FH) to FHbp was thought to be specific for human or chimpanzee FH. However, in a previous study an amino acid polymorphism in rhesus macaque FH domain 6, tyrosine at position 352 (Y352) was associated with high binding to FHbp, whereas histidine at position 352 (H352) was associated w...

Capacity design procedure for the earthquake-resistant reinforced concrete (RC) structures is effective when actual member capacities do not greatly exceed the assumed design capacities. Moreover, RC members are expected to undergo large inelastic deformations for adequate seismic energy dissipation. Since flexural capacity and post-yield behavior of an RC member is largely controlled by steel ...

An enzyme-linked immunosorbent assay (ELISA) has been developed for the titration of rickettsial antibodies in human and animal sera. Two preparations of soluble typhus-group antigens were obtained from Rickettsia typhi and Rickettsia prowazekii by ether extraction: a standard antigen from infected yolk sacs (YS antigen) and one free of yolk sac contaminants from Renografin-purified rickettsiae...

One of the possible ways to ensure future food needs of an increasing world population involves the better water use through the development of crop varieties which need less water and are more tolerant to drought. In order to study the response of twenty landraces of bread wheat to drought stress, an experiment was conducted in a randomized complete block design with three replications under t...

One of the possible ways to ensure future food needs of an increasing world population involves the better water use through the development of crop varieties which need less water and are more tolerant to drought. In order to study the response of twenty landraces of bread wheat to drought stress, an experiment was conducted in a randomized complete block design with three replications under t...