Dissolution studies have become matter of great significance because, in most cases, drug dissolution is the rate-limiting step in the absorption process. As occurs with solid oral dosage forms, heterogeneous disperse systems (suspensions) could also have some problems with their in vitro dissolution. The dissolution behavior of four different brands of cefadroxil extemporaneous suspensions ava...

Here we describe biosensors that provide readouts for protein stability in the cytosolic compartment of prokaryotes. These biosensors consist of tripartite sandwich fusions that link the in vitro stability or aggregation susceptibility of guest proteins to the in vivo resistance of host cells to the antibiotics kanamycin, spectinomycin, and nourseothricin. These selectable markers confer antibi...

We have studied the problem of phase stability in NiPt alloy system. We have used the augmented space recursion based on the TB-LMTO as the method for studying the electronic structure of the alloys. In particular, we have used the relativistic generalization of our earlier technique. We note that, in order to predict the proper ground state structures and energetics, in addition to relativisti...

The present study evaluated effects of exercise training on the proprioception sensitivity, postural stability, and the likelihood of slip-induced falls. Eighteen older adults (6 in balance, 6 in weight, and 6 in control groups) participated in this study. Three groups met three times per week over the course of eight weeks. Ankle and knee proprioception sensitivities and postural stability wer...

Metallabenzyne has attracted considerable interest from theoreticians and experimentalists since its first isolation in 2001. However, metallasilabenzyne, formed by the replacement of the carbyne carbon with a silicon atom in metallabenzyne, has never been reported either theoretically or experimentally. Here we carry out density functional theory (DFT) calculations on this system for the first...

This is a project report from the Power Systems Engineering Research Center (PSERC). PSERC is a multi-university Center conducting research on challenges facing a restructuring electric power industry and educating the next generation of power engineers. More information about the center can be found at the Center's website: Notice Concerning Copyright Material PSERC members are given permissio...

in order to study on adaptability and grain yield stability of eight bread wheat cultivars (alvand, alamout, zarrin, navid, azar 2, sabalan, omid and bezostiya), a rcbd experiment was conducted during three cropping seasons (2007-2010) at six locations (sanandaj, gorveh, marivan, divandarreh, saggez and baneh). simple analysis of variance (anova) and combined anova for three years in each locat...

in the past, rock slope stability analysis were performed either graphically or using a hand-held calculator, but nowadays there are variety of slope stability analysis which can be used according to the field condition and potential failure mode. in 2-d analysis, effect of convex and concave walls are neglected, however concave slopes are believed to be more stable than straight walls due to t...