Congenital lipoid adrenal hyperplasia (CLAH) is caused by mutations to the steroidogenic acute regulatory protein (StAR) gene associated with the inability to synthesize all adrenal and gonadal steroids. Inadequate treatment in an infant with this condition may result in sudden death from an adrenal crisis. We report a case in which CLAH developed in Korean siblings; the second child was prenat...

In adrenal zona glomerulosa cells, the calcium messenger system is the major signaling mechanism activated by physiological stimulators of aldosterone production. We present here evidence for a dual site of action of the calcium signal: 1) Calcium influx into the mitochondrion is a prerequisite to the activation of steroidogenesis. This calcium entry leads to a rise in mitochondrial calcium con...

Poly(γ-4-((2-(piperidin-1-yl)ethyl)aminomethyl)benzyl-l-glutamate) (PPABLG), a cationic helical polypeptide, has been recently developed by us as an effective non-viral gene delivery vector. In attempts to elucidate the effect of molecular architecture on the gene delivery efficiencies and thereby identify a potential addition to PPABLG with improved transfection efficiency and reduced cytotoxi...

In this paper we investigate the stability of one-sided perturbation to g-frame expansions. We show that if $Lambda$ is a g-frame of a Hilbert space $mathcal{H}$, $Lambda_{i}^{a}=Lambda_{i}+Theta_{i}$ where $Theta_{i} in mathcal{L}(mathcal{H},mathcal{H}_{i})$, and $widetilde{f}=sum_{i in J}Lambda_{i}^{star}widetilde{Lambda}_{i}^{a}f$, $widehat{f}=sum_{i in J}(Lambda_{i}^{a})^{star}widetilde{Lam...

Some years ago, we found that Axial organ (AO) cells exerted an induced and spontaneous cytotoxicity against SP2 MBL2 mouse tumoral cells. Recently, discovered a sea star Igkappa gene with immune properties. This was first, inserted in CMV (cytomegalovirus) finally plasmid called « young » plasmid. In the present experiment IGKappa cloned HeK human to produce specific protein. The induced« prot...

let $g$ be a group. the order graph of $g$ is the (undirected)graph $gamma(g)$,those whose vertices are non-trivial subgroups of $g$ and two distinctvertices $h$ and $k$ are adjacent if and only if either$o(h)|o(k)$ or $o(k)|o(h)$. in this paper, we investigate theinterplay between the group-theoretic properties of $g$ and thegraph-theoretic properties of $gamma(g)$. for a finite group$g$, we s...

a graph g = (v,e) with p vertices and q edges is said to be a total mean cordial graph if there exists a function f : v (g) → {0, 1, 2} such that f(xy) = [(f(x)+f(y))/2] where x, y ∈ v (g), xy ∈ e(g), and the total number of 0, 1 and 2 are balanced. that is |evf (i) − evf (j)| ≤ 1, i, j ∈ {0, 1, 2} where evf (x) denotes the total number of vertices and edges labeled with x (x = 0, 1, 2). in thi...

in order to investigation of collembola fauna, several soil and leaf litter sampling were carried out during 2011 in kermanshah regions and species were extracted by berlise funnel. in sum, eight species from eight genera from seven families were collected and identified. the species characterized by one star (*) are new for kermanshah fauna. the species characterized by two star (**) are repor...

This paper discusses the preservation of some stochastic orders between two interdependent series and parallel systems when the survival and distribution functions of all components switch to the exponentiated model. For the series systems, the likelihood ratio, hazard rate, usual, aging faster, aging intensity, convex transform, star, superadditive and dispersive orderings, and for the paralle...