Abstract In this paper, a two-stage block hypothesis testing following the idea of Fan, Lin and Cheng (2004) is proposed for massive data regression analysis. Variables selection criteria incorporating with classical stepwise procedure are also developed to select significant explanatory variables. Simulation study confirms that our approach is more accurate in the sense of achieving the nomina...

The Italian Federation of Healthcare Trusts and Municipalities promoted a national initiative (LITIS, Italian acronym for: Levels of Technological Innovation in Healthcare), to assist its members in the governance of the eHealth phenomenon. The LITIS model spans over the complete spectrum of the eHealth support to care and administrative processes, from two perspectives: the Functions F (servic...

A stepwise degradation of the oligosaccharide part of moenomycin A (2) was performed. The degradation products were assayed for antibiotic activity both in vivo and in an E.coli cell-free system. Units E, F, G, H, and I have been found -to be essential for full biological (in vitro) activity. _It is suggested that 2 is a competitive inhibitor of the peptidoglycan polymerase.

In this paper, we describe an interface to display texts in a fashion adapted to dyslexic readers. In order to help the reading task, we designed several tools geared towards the specific difficulties of this population, e.g. a tendency to lose one’s place within the text, a fluctuating attention or a difficulty to access the syllable level of the words, a process known to be used with new or i...

Model trees are tree-based regression models that associate leaves with linear regression models. A new method for the stepwise induction of model trees (SMOTI) has been developed. Its main characteristic is the construction of trees with two types of nodes: regression nodes, which perform only straight-line regression, and splitting nodes, which partition the feature space. In this way, intern...

Policy-basedmanagement is an approach to the management of sys-tems with respect to issues such as security, access control and trustby the enforcement of policy rules. This paper addresses the problemof integrating the requirements imposed by a policy with the systemdevelopment process. In order to take a policy specification into ac-count in the development of a system spe...

This article contains a short introduction to the Matlab package for estimating change-points in stepwise signals. In the first section, we will outline the theoretical framework of the marginal Likelihood estimator as formulated in Du, Kao and Kou (2015). The second section contains a brief introduction of the Matlab-implementation of this method. In the third section, we will demonstrate the ...

This paper presents two polynomial time algorithms for the constant capacitated lot sizing problem with a batch production. We give several optimality properties for the general problem. Assuming constant production capacity, constant batch size and WagnerWhitin cost structure, we derive O(T ) and O(T ) time algorithms respectively for the case with production capacity multiple of the batch siz...

Uncertainty and sensitivity analysis results obtained in the 1996 performance assessment (PA) for the Waste Isolation Pilot Plant (WIPP) are presented for two-phase flow in the vicinity of the repository under disturbed conditions resulting from drilling intrusions. Techniques based on Latin hypercube sampling, examination of scatterplots, stepwise regression analysis, partial correlation analy...

True stress (·)­true strain (3⁄4) relationships until just before fracture, i.e., the plastic deformation limit, were estimated by the stepwise tensile test and the Bridgman equation for various metals and alloys with different crystal structures. The estimated ·­3⁄4 relationships were different from the nominal stress­strain curves including the conventional tensile properties. In the relation...