Myocardial bridge is a benign congenital anomaly in which a segment of major epicardial coronary arteries descends into the myocardium for a variable distance. Myocardial bridge is most often single and located in the middle part of the left anterior descending artery. The presence of more than one myocardial bridge in coronary arteries is very rare. We present a patient with more than one myoc...

scour around bridge piers is one of the most important fields of hydraulic research. local scour around bridge piers and abutment is one of the main reasons of bridge failures. in the field of scour at the bridges, researches are more focus on scour of piers in compare with abutment. while the available information on the bridge failures required cost, the major problems are related to abutment...

Abstract In Simply supported bridge, superstructure and substructure are separated by the expansion joint bearing. Integral bridge (IB), deck is casted monolithically with abutment wall. bridges have increased redundancy, which improves its seismic performance. Bridge fails may fail due to failure of bearing, non‐availability seating width does not occur in IB. The single pile analysis performe...

In striated muscle thin filament activation is initiated by Ca(2+) binding to troponin C and augmented by strong myosin binding to actin (cross-bridge formation). Several lines of evidence have led us to hypothesize that thin filament properties may limit the level and rate of force development in cardiac muscle at all levels of Ca(2+) activation. As a test of this hypothesis we varied the cros...

This paper presents a three-dimensional nonlinear degrading stiffness model capable of capturing stiffness degradation in bilateral directions for earthquake response analyses of reinforced concrete bridges. Stiffness degradations due to flexural and shear damage are considered. The model can trace the progress of damage from initial failure through gradual degradation of the member stiffness d...

The giant protein titin is responsible for the elasticity of nonactivated muscle sarcomeres. Titin-based passive stiffness in myocardium is modulated by titin-isoform switching and protein-kinase (PK)A- or PKG-dependent titin phosphorylation. Additional modulatory effects on titin stiffness may arise from disulfide bonding under oxidant stress, as many immunoglobulin-like (Ig-)domains in titin'...

Tissue cells are in a state of permanent mechanical tension that is maintained mainly by myosin II minifilaments, which are bipolar assemblies of tens of myosin II molecular motors contracting actin networks and bundles. Here we introduce a stochastic model for myosin II minifilaments as two small myosin II motor ensembles engaging in a stochastic tug-of-war. Each of the two ensembles is descri...