Helicobacter pylori is the microbial agent most responsible for gastro-duodenal ulcer and chronic gastritis, which can develop into carcinoma of stomach. This study was performed in Wad Medani Teaching Hospital, Sudan to detect stomach samples, evaluate performance tests used, were histological stains PCR. Gastric biopsies obtained from 105 referred patients during endoscopy, fixed specimens ex...

papers are surgical, there is a large number dealing with internal medicine, pathology, experimental bacteriology and neurology. It is obviously impossible for a single reviewer to deal with such diverse subjects and if the surgical papers seem to receive undue attention in this notice, it is not because those on medicine are not of equal importance and interest. Carman has an interesting paper...

BACKGROUND Korean red ginseng (KRG) is a ginseng that has been cultivated and aged for 4-6 years or more, and goes through an extensive cleaning, steaming and drying process. KRG contains more than 30 kinds of saponin components and has been reported as having various biological properties, such as anti-fatigue action, immune restoration, and neurovegetative effect. The purpose of this study wa...

Ceramides have emerged as key participants in the signaling pathway of cytokines and apoptosis. We previously revealed that phorbol 12-myristate 13-acetate (PMA) induced experimental ulcers in rat gastric mucosa. In this study, we investigated the role of ceramide in ulcer formation and its relation to the activation of transcription factors and apoptosis. PMA was subserosally injected to rat g...

A 72-year-old-woman, with a history of resection of tracheal (AL) amyloidosis at age 61 and biopsy-based diagnosis of gastric amyloidosis at age 68, was admitted to our hospital. No amyloid deposits had been detected in any other organ and multiple myeloma had been excluded. Gastroscopy showed several findings, including ulcerative lesions mimicking advanced cancer, submucosal tumor-like lesion...

Vogiagis, Daphne, Eric M. Glare, Aileen Misajon, Wendy Brown, and Paul E. O’Brien. Cyclooxygenase-1 and an alternatively spliced mRNA in the rat stomach: effects of aging and ulcers. Am J Physiol Gastrointest Liver Physiol 278: G820–G827, 2000.—Prostaglandins play a critical role in gastric mucosal cytoprotection and decrease progressively with age. Cyclooxygenase (COX), the rate-limiting enzym...

A double gene dose of mutant alleles at either the W or Sl locus produces the pleiotropic effects of anemia, sterility, lack of hair pigmentation, and lack of tissue mast cells. Coincidental development of forestomach papilloma and prepyloric ulcer was observed in about 40% of nontreated (WB X C57BL/6) F1-W/Wv mice raised in our laboratory. The stomach lesions of the W/Wv mice could be detected...

The results of a prospective inquiry into the aspirin taking habits of a consecutive series of 118 patients admitted to a large general hospital with acute perforation of peptic ulcer are presented. The series shows considerable increase in the proportion of females to males and of ulcers of the stomach compared to pyloro-duodenal perforations in contrast to British experience. Forty-five per c...

Peptic ulcers and gastritis are a serious and growing health problem in the whole world. Ulcers affect about 5 million Americans each year, and more than 40,000 people annually have ulcer-related surgery. Each year, approximately 15,000 people in the Unites States die of ulcer-related complications, the worst of which are an internal bleeding and perforation. A peptic ulcer is an open sore or l...