Streptomyces sp. US 24 and Streptomyces sp. TN 58, two strains producing interesting bioactive molecules, were successfully transformed using E. coli ET12567 (pUZ8002), as a conjugal donor, carrying the integrative plasmid pSET152. For the Streptomyces sp. US 24 strain, two copies of this plasmid were tandemly integrated in the chromosome, whereas for Streptomyces sp. TN 58, the integration was...

It has recently been proposed by Wellington et al. that the genus Kitasatosporia Omura, Takahashi, Iwai and Tanaka (9) is a synonym of the genus Streptomyces, and four validly published species, Kitasatosporia setae (9), Kitasatosporia griseola (12), Kitasatosporia phosalacinea (12) and Kitasatosporia mediocidica (3), have been transferred to the genus Streptomyces as new combinations, Streptom...

the streptomycetes are gram positive bacteria with a filamentous form that present in a wide variety of soil including composts, water and plants. the most characteristic of streptomycetes is the ability to produce secondary metabolites such as antibiotics. they produce over two-thirds of the clinically useful antibiotics of natural origin (e.g., neomycin and chloramphenicol. another characteri...

produced by mutants of Streptomyces peucetius^ , the daunorubicin2) producing microorganism, led to the discovery of doxorubicin (adriamycin)3) and other new anthracyclines4~8). By further mutagenic treatment of Streptomyces peucetius var. aureus, sl mutant of Streptomyces peucetius producing 4Odemethyl1 1 deoxydoxorubicin and analogues7), we have recently isolated other new mutant strains. Amo...

Background and Purpose: Cutaneous infections arise from a homogeneous group of keratinophilic fungi, known as dermatophytes. Since these pathogenic dermatophytes are eukaryotes in nature, use of chemical antifungal agents for treatment may affect the host tissue cells. In this study, we aimed to evaluate the antifungal activity of Actinomyces species against Trichophyton mentagrophytes (abbrevi...

Protoplast fusion was investigated as a technique for genetically manipulating two lignin-degrading Streptomyces strains, Streptomyces viridosporus T7A and Streptomyces setonii 75Vi2. Four of 19 recombinants tested showed enhanced production of acid-precipitable polymeric lignin (APPL), producing 155 to 264% more APPL from corn stover lignocellulose than was produced by the wild-type S. viridos...

Fish plays an important role in the Bangladeshi diet, constituting the main and often irreplaceable animal food in rural households. Fish consumption is dominated by wild small indigenous fish species (SIS). The vitamin A content in SIS varies from less than 100 to more than 2,500 retinol equivalents (RE) per 100 g of raw edible parts. This study assessed the dietary contribution of vitamin A, ...

Safety Instrumented Systems (SIS) as defined in IEC 61508 and IEC 61511 are very important for the safety of offshore oil & natural gas installations. SIS typically include the Emergency Shutdown System (ESD) that ensures that process systems return to a safe state in case of undesirable events. Partly as a consequence of the evolving “Integrated Operations” concept, a need is emerging for remo...

Since mean-field approximations for susceptible-infected-susceptible (SIS) epidemics do not always predict the correct scaling of the epidemic threshold of the SIS metastable regime, we propose two novel approaches: (a) an ε-SIS generalized model and (b) a modified SIS model that prevents the epidemic from dying out (i.e., without the complicating absorbing SIS state). Both adaptations of the S...

We present the development of a low noise 1.2 THz and 1.4 THz SIS mixers for heterodyne spectrometry on the Stratospheric Observatory For Infrared Astronomy (SOFIA) and Herschel Space Observatory. This frequency range is above the limit for the commonly used Nb quasi particle SIS junctions, and a special type of hybrid Nb/AlN/NbTiN junctions has been developed for this project. We are using a q...