Collagen provides cardiovascular tissues with the ability to withstand haemodynamic loads. A similar network is essential to obtain in tissue-engineered (TE) samples of the same nature. Yet, the mechanism of collagen orientation is not fully understood. Typically collagen remodelling is linked to mechanical loading. However, TE constructs also show an oriented collagen network when developed un...

Muscle responses to tetanic electrical stimulation were detected by the non-invasive tensiomyographic (TMG) measuring method. The main objective of this study was to find out whether the TMG measuring method is suitable for monitoring the unfused tetanus (stimulation frequencies ranging from 1 Hz to the fusion frequency (ff)--the frequency at which tetanus occurs), and whether this monitoring p...

Bonding synthetic fibres to metals improve strength, durability, and corrosion resistance is a prevalent practise in the automotive, marine, aerospace industries. Lap shear adhesion, measurement of bonding strength between composites metallic substrates, essential for structural integrity. The emergence natural fibre as sustainable alternatives makes it investigate their lap behaviour effect vo...

The micro/nano structural evolution before and after tensile loading, fatigue and ultimately, failure has been studied by Raman microspectroscopy for PA66, PP, PBO and PET single fibres and precursors, using two probes : low wavenumber collective modes at <150 cm as representative of the crystalline and amorphous chains and stretching and bending modes, as representative of the C-C bond local b...

Structure and function of peripheral nerve in early insulin deficient streptozotocin diabetic rat were examined. Quantitative studies of myelinated fibres from electron micrographs showed that the fibre calibre and slope coefficients of regression lines between axon and myelin areas were reduced and quantitation of unmyelinated fibres revealed a 40% reduction in area fraction of smooth endoplas...

Spider silk shows great potential as a biomaterial: in addition to biocompatibility and biodegradability, its strength and toughness are greater than native biological fibres (e.g. collagen), with toughness exceeding that of synthetic fibres (e.g. nylon). Although the ultimate tensile strength and toughness at failure are unlikely to be limiting factors, its yield strain of 2% is insufficient, ...

The mechanisms controlling the conversion of spider silk proteins into insoluble fibres, which happens in a fraction of a second and in a defined region of the silk glands, are still unresolved. The N-terminal domain changes conformation and forms a homodimer when pH is lowered from 7 to 6; however, the molecular details still remain to be determined. Here we investigate site-directed mutants o...

Studies in experimental diabetic rat attribute the acute reversible nerve conduction defect as well as the early structural abnormalities of the node of Ranvier and myelinated axons to changes in nerve metabolism secondary to hyperglycaemia and activation of the pol yo1 pathway.’-8 The early readily reversible slowing of nerve conduction velocity in the diabetic rats correlates with a decrease ...

Fibre-reinforced shotcrete (sprayed concrete) is one of the major components in support system for tunnels hard rock. Several empirical design methodologies have been developed over years due to complexity and many uncertainties involved rock design. Therefore, this paper aims highlight how choice methodology fibre type impacts structural capacity lining emission greenhouse gases (GHG). The sta...

&#x0D; Steel fibres are used in high amounts high-performance steel fibre reinforced cementitious composite (HPSFRCCs) and ultra-high-performance (UHPSFRCCs) to enhance its structural performance. Due the amount randomly distribution of matrix a level damage aesthetic mechanical response may be expected for structures under chloride exposition. This work aims assess behaviour uncracked HPSFRCCs...