toxic effects of malathion and endosulfan to fertile chicken eggs were determined. in-jection of 1.25, 2.5, 5.0 and 10.0 mg/egg of malathion into yolk sac of fertile eggs prior to incubation caused mortality of 10.0, 30.0, 83.33 and 93.33% respectively. similar trend was observed with injection of endosulfan doses. malathion and endosulfan at 1.25 mg/egg caused no pronounced ld50 increase in mo...

This study investigated the effects of sub-chronic administration of sub-lethal doses of amitraz on some testicular parameters of Albino rats. Twenty-four adult male Albino rats (100 ± 10 g) randomly assigned into four groups were used for the study. Groups A, B and C received 10.0, 2.0 and 0.4 mg/kg amitraz in 10 ml/kg water while group D received equivalent volume of water orally and daily fo...

Background: There is unprecedented increase in the processing and packaging of many plant materials into food supplements, herbal medicine, skincare and cosmetic products for human needs. Baphia nitida is used for topical skincare products. Toluene, a toxic aromatic solvent, is increasingly being used in the production of these skincare and cosmetic products in many industries. This study ass...

A laboratory level microcosm analysis of the impacts of ocean acidification on the environmental stress biomarkers in Portunus pelagicus (Linneaus 1758)exposed to a series of pH regimes expected in the year 2100 (pH 7.5 and 7.0) and leakage from a sub-seabed carbon dioxide storage site (pH 6.5 - 5.5) was carried out. Levels of the antioxidant enzyme catalase, the phase II detoxificatio...

A study was conducted to determine the growth performance and bioaccumulation and tolerance of metal mixture toxins in five fish species including Labeo rohita, Catla catla, Cirrhina mrigala, Hypophthalmichthys molitrix and Ctenopharyngodon idella separately, under chronic exposure of metal mixture (Fe + Zn + Pb) at sub-lethal concentrations (1/3 of LC50) for 12 weeks period. Moreover, response...

Acute Radiation Syndrome (ARS) may lead to cancer and death and has few effective countermeasures. Efficacy of synthetic PIF treatment was demonstrated in preclinical autoimmune and transplantation models. PIF protected against inflammation and mortality following lethal irradiation in allogeneic bone marrow transplant (BMT) model. Herein, we demonstrate that PIF imparts comprehensive local and...

In view of the neurotoxic effects induced by chlordecone an attempt is made to study the in vivo effect of this organic insecticide on rat brain based nitric oxide synthase (NOS) activity. Rats cerebellum, hypothalamus, midbrain, straiatum, hippocampus, cerebral cortex and medulla oblongate receiving sub-lethal and lethal doses of chlordecone showed decreased levels of their constitutive NOS ac...