BACKGROUND Maintaining blood pressure (BP) and heart rate (HR) after laryngoscopy and tracheal intubation has always been a concern in injured patients. Opioids can attenuate or stop an increase in these two parameters if administered with proper doses or targets in target-controlled infusion (TCI). Remifentanil and sufentanil are widely used for this purpose because their cardiac side effects ...

OBJECTIVE Laryngoscopy and tracheal intubation may cause significant cerebral and systemic hemodynamic responses. Many drugs have been shown to be effective in modifying these hemodynamic responses, including fentanyl, sufentanil, alfentanil and remifentanil. The purpose of the current study was to compare the efficacy of fentanyl, sufentanil, alfentanil and remifentanil on blunting cardiovascu...

We studied the disposition of sufentanil in 10 patients undergoing renal transplantation, and compared the data with those from eight healthy anaesthetized patients undergoing lower abdominal surgery. Patients received sufentanil 2.5 micrograms kg-1 as part of a balanced anaesthetic technique. Central venous blood samples were collected at intervals up to 600 min, and plasma sufentanil concentr...

BACKGROUND In the recent decades controlling postoperative pain has become a popular topic as it leads to the patients' wellbeing and improved life quality, while it reduces the costs for both patients and medical facilities. OBJECTIVES This study aimed at comparing intravenous magnesium sulfate versus intravenous sufentanil on the duration of analgesia and postoperative pain in patients unde...