Introduction: Cardiovascular disease is a major challenge of global health. The modern treatment of coronary artery disease (CAD) is based on the development of novel cardiac interventions. In 1977, the first percutaneous coronary intervention (PCI) was performed, initiating the era of percutaneous revascularization. The field of cardiac intervention evolves rapidly, and the need to continuosly...

Oxidative killing by neutrophils, a primary defense against surgical pathogens, is directly related to tissue oxygenation. We tested the hypothesis that supplemental inspired oxygen or mild hypercapnia (end-tidal PCO2 of 50 mm Hg) improves intestinal oxygenation. Pigs (25 +/- 2.5 kg) were used in 2 studies in random order: 1) Oxygen Study: 30% versus 100% inspired oxygen concentration at an end...

Carbon monoxide (CO) is the most common cause of poisoning and poisoning-related death in the United States. It is a tasteless and odorless poisonous gas produced from incomplete combustion of hydrocarbons, such as those produced by cars and heating systems. CO rapidly binds to hemoglobin to form carboxyhemoglobin, leading to tissue hypoxia, multiple-organ failure, and cardiovascular collapse. ...

e o o o o . e o o o o o o o o o o o o o o o o V111 CHAPTER I© INTRODUCTION © © © © © © © © © o o o e o o o o o 1 Purpose of the Study . . . . o . 3 Hypothesis of the Study . . . . . . . . . . 4 Significance of the Problem . . . . . . . . 4 Conceptual Framework . . . . . . . . . . . . 5 2. REVIEW OF THE LITERATURE © © © ., . . © . . . „ 9 Controlled Supplemental Oxygen Therapy . . . 9 Nasal.Cann...

Background: For patients with chronic obstructive pulmonary disease (COPD), an increase in exercise tolerance and ability to perform activities of daily living (ADLs) can mean an improved quality of life with fewer exacerbations and lower health care expenses. We evaluated a wearable, noninvasive open ventilation (NIOV) system designed to enhance exercise capacity and increase mobility. Methods...

BACKGROUND AND OBJECTIVES The Transfusion-Related Acute Lung Injury (TRALI), is defined as noncardiogenic pulmonary edema temporally related to transfusion therapy, evolving with ventilation necessity mechanics in the great majority of the cases. This objective of this study was to present case of TRALI in the immediate postoperative of neurosurgery. CASE REPORT We describe the case of a pati...

Supplemental oxygen improves exercise tolerance of normoxemic and hypoxemic chronic obstructive pulmonary disease (COPD) patients. We determined whether nonhypoxemic COPD patients undergoing exercise training while breathing supplemental oxygen achieve higher intensity and therefore improve exercise capacity more than patients breathing air. A double-blinded trial was performed involving 29 non...

objectives the purpose of this study was to evaluate the effects of normobaric hyperoxia on clinical neurological outcomes of patients with severe traumatic brain injuries. we used the glasgow outcome scale (gos), barthel index, and modified rankin scale (mrs) to measure the outcomes of patients with tbi. patients and methods sixty-eight consecutive patients with severe tbi (mean glasgow coma s...

BACKGROUND Patient-controlled analgesia is associated with potentially fatal opioid-related respiratory depression. Opioids are a well-recognized cause of respiratory depression. However, in the postoperative patient, unrecognized pulmonary disease may lead to retention of carbon dioxide, which is further antagonized by opioids and may lead to life-threatening respiratory depression. Therefore,...