Silicon-based micro- and nanoparticles have gained popularity in a wide range of biomedical applications due to their biocompatibility and biodegradability in vivo, as well as their flexible surface chemistry, which allows drug loading, functionalization and targeting. Here, we report direct in vivo imaging of hyperpolarized (29)Si nuclei in silicon particles by magnetic resonance imaging. Natu...

A controllable and high-yield surface functionalization of silicon microchannels using layer-by-layer (LbL) self-assembly of SiO2 nanoparticles (SNPs) is presented. The application of SNPs (45 nm average diameter) coating as a stationary phase for chromatographic separation is also demonstrated with surface functionalization using chloroalkylsilanes. This method facilitates a simple, low-cost, ...

A new class of nanostructured hybrid materials is developed by direct grafting of a model thiophene-based organic dye on the surface of 3C-SiC/SiO2 core/shell nanowires. TEM-EDX analysis reveals that the carbon distribution is more spread than it would be, considering only the SiC core size, suggesting a main contribution from C of the oligothiophene framework. Further, the sulfur signal found ...

The present work presents the latest advances for the modification of TiO2 surfaces by their functionalization with complex organic molecules through a scCO2 strategy. Two strategies were followed: the first strategy involved the deposition under anhydrous conditions onto the TiO2 surface of laboratory prepared silane containing nitro-phenyl and nitro-formyl groups, leading to the products desi...

In recent years, advanced nanocomposite materials have been widely used in a large number of commercially valuable industrial applications such as in automobile, marine coatings, aerospace, and construction industries. The nanocomposites are made up of organic polymers and inorganic nanomaterials using different processing techniques. For example, metal, metal oxide, and carbon-based nanomateri...

Surface-initiated polymerization has been used to grow thick, uniform poly(methyl methacrylate) films on nanocantilever sensors. Cantilevers with these coatings yielded significantly greater sensitivity relative to bare devices as well as relative to devices that had been coated with drop-cast polymer films. The devices with surface-initiated polymer films also demonstrated high selectivity tow...

despite development of new approaches for the treatment of cancer disease, it is the second cause of mortality in world. annually, 30000 persons die in iran due to cancer diseases. eighty percent of cancer patients are children which about 50% children lead to death. given the high rate of cancer-related death, the new approaches for prevention, control, early diagnosis, and treatment of this d...

We report on an exceedingly mild chemical functionalization of hydrogen-terminated Si(100) with unactivated and unprotected bifunctional α,ω-dialkynes. Monolayer formation occurs rapidly in the dark, and at room temperature, from dilute solutions of an aromatic-conjugated acetylene. The method addresses the poor reactivity of p-type substrates under mild conditions. We suggest the importance of...

Restricted oxygen diffusion can result in central cell necrosis in engineered tissue, a problem that is exacerbated when engineering large tissue constructs for clinical application. Here we show that pre-treating human mesenchymal stem cells (hMSCs) with synthetic membrane-active myoglobin-polymer-surfactant complexes can provide a reservoir of oxygen capable of alleviating necrosis at the cen...

An efficient protocol for post-functionalization of organo-imido polyoxometalates is developed via creating a remote tertiary “N” atom over the surface of organo-imido hexamolybdates and subsequently post-functionalizing it with the help of allyl or alkyl halides to afford stoichiometric, “in situ” crystalline products at moderate temperatures. The parent organo-imido product 2 and post-functio...