Hydrophobins, adhesive proteins produced by filamentous fungi, have been described as the most surface active proteins known and show extraordinary properties regarding formation of surfaces. Hydrophobins have roles in the growth and development of the fungi including function in adhesion to surfaces, reducing surface tension for aerial growth and spore hydrophobicity and to aid spreading of ae...

BACKGROUND Aggregation of unfolded proteins occurs mainly through the exposed hydrophobic surfaces. Any mechanism of inhibition of this aggregation should explain the prevention of these hydrophobic interactions. Though arginine is prevalently used as an aggregation suppressor, its mechanism of action is not clearly understood. We propose a mechanism based on the hydrophobic interactions of arg...

Recent progress in simulating the properties of interfacial water at hard hydrophobic and hydrophilic surfaces is reviewed and compared to results for the air/water interface. The authors discuss static properties such as the equilibrium contact angle, the depletion layer thickness, and the orientation of interfacial water molecules. Relations between these properties, e.g., the relation betwee...

The effects of low-concentration monorhamnolipid (monoRL) on the adsorption of Pseudomonas aeruginosa ATCC 9027 grown on glucose or hexadecane to glass beads with hydrophobic or hydrophilic surfaces was investigated using batch adsorption experiments. Results showed that adsorption isotherms of the cells on both types of glass beads fitted the Freundlich equation better than the Langmuir equati...

      Losartan potassium is a well known orally active non-peptide angiotensin II receptor antagonist. Losartan potassium and its principle active metabolites block the vasoconstrictor and aldosterone secreting effect of angiotensin II by selectively blocking the binding of angiotensin II to AT1 receptors. The drug is reported to promote the decrease in ventricular hypertrophy, salt ...

In this work, the hydrophobic modification of TiO2 nanoparticles (HTiO2) was carried out by reacting with dodecylphosphonic acid (DDPA) and hexylamine solution. A facile approach of the self-assembly technique was used for the coating of hydrophobic HTiO2 layer over the microporous polypropylene (PP) membrane. The self-assembled layer was formed between the interface of trimesoyl chloride (TMC)...

The effect of colonial variation and growth at pH 7.2 or pH 6.0 on the surface properties of Neisseria gonorrhoeae was assessed by the use of two-phase partitioning and hydrophobic interaction chromatography. Cells grown at pH 7.2 tended to be both hydrophobic and to possess a slight negative charge. Growth at pH 6.0 appeared to decrease hydrophobicity and to increase the negative surface charg...

Although caveolins normally reside in caveolae, they can accumulate on the surface of cytoplasmic lipid droplets (LDs). Here, we first provided support for our model that overaccumulation of caveolins in the endoplasmic reticulum (ER) diverts the proteins to nascent LDs budding from the ER. Next, we found that a mutant H-Ras, present on the cytoplasmic surface of the ER but lacking a hydrophobi...

An "inorganic micelle" structure that has a hydrophilic cavity and hydrophobic surface has been synthesized. The inorganic micelles possess large surface area and controllable hydrophobic/hydrophilic interface. It shows high catalytic efficiency and great recyclability in the bromination of alcohols. This work suggests that inorganic micelles may be suitable for selective organic syntheses as w...

X-ray reflectivity measurements reveal a significant dewetting of a large hydrophobic paraffin surface floating on water. The dewetting phenomenon extends less than 15 A into the bulk water phase and results in an integrated density deficit of about one water molecule per 25-30 A(2) of water in contact with the paraffin surface. The results are supported by molecular dynamics simulations and re...