The spun packed cell volume (PCV, hematocrit) is a key measurement on which are based hematology instrument calibration, reference range determination, and assignment of values to calibrators/controls. In 2001, the International Council for Standardization in Haematology (ICSH) recommended a Reference PCV method, which is fully traceable to the ICSH reference hemoglobin method. Because of its c...

The metamodeling has been widely used for design optimization problems by building surrogate models for compute-intensive simulation models. Among metamodeling methods, the Kriging method has gained significant interest for its accuracy in developing the surrogate model. However, in traditional Kriging methods, the optimization methods that are used to obtain the optimum correlation parameter d...

Uranium mononitride (UN) is a candidate fuel material for light water reactors with higher uranium (U) loading and thermal conductivity than dioxide (UO2). However, the sintering of UN pellets challenging as powder particles oxidize rapidly at high temperatures unless oxygen concentration extremely low. Oxidation during either reduces relative density sintered pellet or disintegrates to powder....

In this paper we present a compact review on the mostly used techniques for computational reduction in numerical approximation of partial differential equations. We highlight the common features of these techniques and provide a detailed presentation of the reduced basis method, focusing on greedy algorithms for the construction of the reduced spaces. An alternative family of reduction techniqu...

The principal problem that affects software development projects is low quality requirements specifications. Low quality requirements specifications make it difficult to develop high quality software. We propose using the Estimated Function Point Counting (EFPC) method of software size estimation as a surrogate process for Requirements Engineering (RE) process, especially for the organizations ...

GAIL E. TUDOR. Survival Analysis Using Primary and Surrogate Endpoints. (Under the direction of TIMOTHY M. MORGAN) Current survival techniques do not provide a good method for handling clinical trials with a large percent of censored observations. Some methods that have been proposed to increase the power of analyses· include covariate adjustment, multivariate models, use of surrogate endpoints...

Background: There has been little interest in the research literature on public opinions regarding assisted conception and surrogacy, particularly in Iran. Nevertheles, the growing evidence shows that problems in adaptation and coping may be related to perceived normative values. Materials and Methods: In this cross sectional study, questionnaires on attitudes to surrogacy were completed by 187...

Currently surrogate data analysis can be used to determine if data is consistent with various linear systems, or something else (a nonlinear system). In this paper we propose an extension of these methods in an attempt to make more speciic classiications within the the class of nonlinear systems. In the method of surrogate data one estimates the probability distribution of values of a test stat...