Background—In patients with severe aortic stenosis who cannot have surgery, transcatheter aortic valve replacement (TAVR) has been shown to improve survival and quality of life compared with standard therapy, but the costs and cost-effectiveness of this strategy are not yet known. Methods and Results—The PARTNER trial randomized patients with symptomatic, severe aortic stenosis who were not can...

BACKGROUND To show the reduction in life expectancy due to smoking and the recovery of normal life expectancy by smoking cessation is useful for tobacco control health policy. METHODS This study included 140,026 males and 156,810 females aged 40-79 years, who were participants of large-scale cohort studies in Japan (Japan Health Center-based Prospective Study [JPHC]-I, JPHC-II, Three-Prefectu...

Purpose of the study Combination antiretroviral therapy (cART) has greatly improved the life expectancy of people living with HIV (PLHIV). A series of cohort studies have predicted near-to-normal life expectancies for PLHIV receiving cART but have not considered the impact of multi-class resistance on long-term survival. Our study aims to project the future life expectancy of PLHIV in a resourc...

This paper aims to discuss the concept of canine guidance in light recent research with regard time extraction restored tooth, crowns representing worst performing restoration at 15 years (66% cumulative survival). Given that upper tooth may be considered 'cornerstone' arch, reasons for this poor performance are discussed by examination existing literature on and other aspects relating preparat...

BACKGROUND Cystic fibrosis (CF) is a common life-shortening genetic disease in which women have been described to have worse outcomes than males, particularly in response to respiratory infections with Pseudomonas aeruginosa. However, as advancements in therapies have improved life expectancy, this gender disparity has been challenged. The objective of this study is to examine whether a gender-...

BACKGROUND Survival from cystic fibrosis is increasing rapidly. Estimates of the extent of this improvement should allow health care facilities to be planned to deal with the expanding population of patients with cystic fibrosis. Estimates of life expectancy are also essential if accurate information on current prognosis is to be given to parents of an affected child, or to prospective parents ...

Abstract Background The aim of elective Abdominal Aortic Aneurysm (AAA) repair is to prevent premature death from rupture. Endovascular Repair (EVAR) 2 trial showed that patients with AAA who are not fit for open do benefit in terms life-expectancy EVAR. In our region, the average life expectancy men above national but controversy remains when offering octogenarians expensive procedures prolong...

Coarctation of the aorta is typically a disease of childhood and early adulthood, and there is a reduced life expectancy in patients who have not undergone correction. Survival to older age is rare, due to severe cardiovascular complications. We describe the case of a woman first diagnosed with coarctation of aorta at an advanced age.

BACKGROUND Many elderly men with high-risk nonmetastatic prostate cancer (HRnMPCa) do not receive radical treatment, despite the high mortality associated with conservative management. OBJECTIVE To investigate how age and comorbidity affect treatment of men with HRnMPCa. DESIGN, SETTING, AND PARTICIPANTS This was an observational nationwide register study during 2001-2012. We identified 19 ...