A novel polypeptide hydrogel has been synthesized by crosslinking poly(L-glutamic acid) (PLG) with poly(ethylene glycol) (PEG). The PLG-PEG hydrogel was shown to be highly hydrophilic, and the extent of swelling varied with pH, increasing at higher ionization of the PLG. Aside from electrostatic effects, such as ion-ion repulsion and internal ion osmotic pressure, circular dichroism studies sho...

Introduction: The current work was aimed to design and synthesize novel crosslinked pH-sensitive gelatin/pectin (Ge/Pec) hydrogels using different polymeric ratios and to explore the effect of polymers and degree of crosslinking on dynamic, equilibrium swelling and in vitro release behavior of the model drug (Mannitol). Methods: The Ge/Pec based hydrogels were prepared using glutaraldehyde as t...

pH-sensitive hydrogels are suitable candidates for oral drug delivery of peptides due to their ability to respond to their environment. We have developed new hydrogels composed of poly(methacrylic acid) (PMAA) grafted with poly(ethylene glycol) (PEG) (P(MAA-g-EG)) which can be used as drug delivery carriers for salmon calcitonin. P(MAA-g-EG) hydrogels were prepared by free radical solution poly...

In the present paper, attention is paid to synthesis and investigation swelling behavior of a superabsorbent hydrogel composite based on Pectin (Pec) and polyacrylonitrile (PAN) in the presence Kaolin powder. The physical mixture of Pec, Kaolin and PAN were hydrolyzed by NaOH solution to yield H-Pec-poly (sodium acrylate-co-acrylamide)/Kaolin superabsorbent hydrogel composite. A proposed mechan...

Abstract When a water drop is placed onto soft polymer network, wetting ridge develops at the periphery. The height of this typically governed by surface tension balanced elastic restoring forces network. However, situation more complex when network swollen with fluid, because fluid may separate from contact line. Here we study separation and deformation line polydimethylsiloxane (PDMS) silicon...

Of all materials, silicon has the highest capacity to store lithium, and is being developed as an electrode for lithium-ion batteries. Upon absorbing a large amount of lithium, the electrode swells greatly, with a volumetric change up to 300%. The swelling is inevitably constrained in practice, often leading to stress and fracture. Evidence has accumulated that the swelling-induced stress can b...

Objectives: To determine the strength and swelling behavior of black cotton soil (expansive soil) using a shredded rubber tyre as an additive. Methods: Series unconfined compressive California Bearing Ratio (CBR) tests were carried out on mixed with 0%, 5%, 10%, 15% tyres, results compared untreated samples. The study also investigated influence characteristics by performing pressure test. Find...