Somatostatin (SST) is a 28-amino-acid cyclic neuropeptide mainly secreted by neurons and endocrine cells. A major interest for SST receptors (SSTR) as target for in vivo diagnostic and therapeutic purposes was born since a series of stable synthetic SST-analouges PET became available, being the native somatostatin non feasible for clinical use due to the very low metabolic stability. The ration...

Serum sialytransferase (SST) levels were determined in patients with various gastrointestinal cancers at different clinical stages. These SST values are significantly elevated over normal healthy controls, and a correlation was observed beteen tumor stage and SST activity. While SST levels rise in patients with increasing tumor burdens, they revert to normal in patients with undetectable tumor ...

The selective loss of somatostatin (SST)-containing interneurons from the hilus of the dentate gyrus is a hallmark of epileptic hippocampus. The functional consequence of this loss, including its contribution to postseizure hyperexcitability, remains unclear. We address this issue by characterizing the actions of SST in mouse dentate gyrus using electrophysiological techniques. Although the maj...

Articles you may be interested in Sensitive dependence of hydrogen Balmer-alpha laser-induced fluorescence signal from hydrogen neutral beam on background magnetic field Recent development of self-interaction-free time-dependent density-functional theory for nonperturbative treatment of atomic and molecular multiphoton processes in intense laser fields Towards the realization of the quantum che...

[1] A new pathway for the negative impact of ENSO on tropical North Atlantic (NAtl) storm activity is examined empirically. Anomalous tropospheric temperatures communicated from the Pacific by wave dynamics are hypothesized to impact storm development by affecting column stability relative to equilibrium with NAtl sea surface temperature (SST). This combines recent teleconnection theory with th...

The activity of sucrose-sucrose-fructosyltransferase (SST), a vacuolar enzyme strongly induced by light in excised leaves of barley (Hordeum vulgare L.), rapidly declined even in continuous light upon feeding of cycloheximide (CHI). The rate of decline was similar to that observed in light-treated leaves that were placed into darkness, in the presence or absence of CHI. The protease inhibitor l...

The Advanced Along-Track Scanning Radiometer (AATSR) onboard Envisat is designed to provide very accurate measurements of sea surface temperature (SST). Using colocated in situ drifting buoys, a dynamical matchup database (MDB) is used to assess the AATSR-derived SST products more precisely. SST biases are then computed. Currently, Medspiration AATSR SST biases are discrete values and can intro...

Ischemia is a primary cause of neuronal death in retinal diseases. The repertoire of expressed transmitter receptors would determine the neurons' responses to ischemic damage, and peptidergic receptors may be involved. With a new in vitro model of the ischemic mouse retina, we investigated whether an altered expression of somatostatin receptors could modulate retinal responses to ischemia. We u...

The sensitivity of long-term averaged air–sea fluxes calculated by a 3D atmospheric general circulation model to SST perturbations of an idealized spatial structure is investigated as a function of the SST perturbation amplitude, spatial scale, latitude, and season. This sensitivity is a dominant, yet largely unknown, parameter determining the stability and variability behavior of ocean-only mo...