Background: The aim of this study was to investigate the effects of nano-eugenol combined with aerobic exercise against the streptozotocin toxicity and inflammatory mediators P38-MAPK, NPY and A-Rα2A in the dorsal root ganglia of diabetic rats. Methods: Twenty-five, 8-week-old Wistar male rats were divided into 5 groups: 1) normal control group (normal model); 2) diabetic control group (diabet...

The use of natural compounds is promising in approaches to prevent and treat cancer. long-term application most currently employed chemotherapy techniques has toxic side effects. Eugenol, a phenolic phytochemical extracted from certain essential oils, an anti-cancer effect. modulation autophagy can promote either the survival or apoptosis cancer cells. Triple-negative (MDA-MB-231) HER2 positive...

The present work describes three spectrophotometric methods for determining two phytoconstituent berberine hydrochloride and eugenol in formulated gels: simultaneous equation method, absorbance correction, zero-crossing derivative method. In the at 263 nm 280 correction method 345 were measured applied to their respective estimation of phosphate buffer emulgel. amplitudes first spectra 252.5 26...

Male oriental fruit flies (Dacus dorsalis) from colonies in Taiwan and Hawaii were evaluated for limit of response to various analogues of methyl eugenol. The results are interpreted in terms of the geometry and allosteric requirements of the antennal receptor that triggers the characteristic methyl eugenol reflex. This receptor has evolved for complementarity to all portions of the methyl euge...

OBJECTIVE This study evaluated the effect of two different eugenol-based root canal sealers on the retention of prefabricated metal posts luted with adhesive resin cement. MATERIALS AND METHODS Thirty prefabricated ParaPosts randomly divided among three groups of 10 each were luted into extracted single-rooted teeth with adhesive resin cement. Two of the groups had been obturated with Gutta-P...

HIGHLIGHTS Eugenol-loaded Eudragit RS100 nanocapsules were suitably obtained and characterized. A simple fast UPLC/MS-MS method for determining eugenol in was developed validated. showed physical stability after 60 days of preparation. may be further used reducing dental sensitivity.

Aspirin eugenol ester (AEE) is a promising drug candidate, which is used for the treatment of inflammation, pain and fever and the prevention of cardiovascular diseases. This study focuses on the effect of AEE on five proteins which are related to inflammation and thrombosis, including cyclooxygenase-1 (COX-1), cyclooxygenase-2 (COX-2), C-reactive protein (CRP), prothrombin (FII) and arachidona...

The chemical variations of the essential oil from the aerial parts of Laurus nobilis L. (Lauraceae) have been studied. Plant material has been harvested at each phenological status (vegetative, before anthesis, full flowering and seed-bearing). The oils were obtained by hydrodistillation of the air-dried samples. Analysis by GC and GC-MS of the essential oils has allowed to identify 39 compound...

The combined effects of using cinnamaldehyde with catechin, quercetin or eugenol against wood decay fungi were examined by comparing their isoeffective concentrations to that of individual compound. Among all combinations, cinnamaldehyde with eugenol revealed the strongest synergy against Laetiporus sulphureus. The synergism was due to the interference of fungal cell wall synthesis and cell wal...