Several observations made over the past year have forged strong molecular links between transcription by RNA polymerase II (Pol II) and pre-mRNA processing. The key findings support the view that the carboxy-terminal domain (CTD) of the large subunit of RNA polymerase II binds directly to protein factors essential for RNA processing. In some cases, there is a clear suggestion that the factors o...

Listening taking over half of the learners’ time and effort (Nunan, 1998), forms a basis for acquiring much of a language. There are factors affecting listening comprehension and its perception, such as the speech rate, phonological properties of the text, the quality of the recording, the learners’ anxiety, and listening comprehension strategies (Goh, 2000; Hamouda, 2013). At the Iran Language...

BACKGROUND Despite national guidelines in 2003 aimed at limiting the recourse to tonsillectomy and/or adenoidectomy (A/T), the latter are among the most frequent pediatric surgeries performed in Italy. Aim of the study is to investigate variability of A/T rates among children of the Veneto Region, Italy. METHODS All discharges of Veneto residents with Diagnosis-Related Groups 57-60 and ICD9-C...

with Vt the volume of the space visited in the simulation and D the dimension. Ω is the solid angle in D-dimensional spherical coordinates and w(r,Ω, t) the weight of the node at position (r,Ω), at time t. For simplicity spherical symmetry of the energy landscape (U(x) = U(r)) will be assumed. For large enough t, w(r, t) is proportional to the stationary solution. Taking U(r) in the units of kB...

In vitro studies were performed in two patients with B-cell chronic lymphocytic leukemia who developed pure red cell aplasia (CLL-PRCA). During the active phase of their red cell aplasia, there was a marked reduction in the numbers of erythroid colony-forming units (CFU-E). Unfractionated sera or separated IgG fractions from these patients did not impair CFU-E proliferation from either autologo...

We used a heteroduplex deletion loop mutagenesis procedure for directing sodium bisulfite-induced mutations to specific sites on viral or plasmid DNA to generate a series of SV40 large T-antigen point mutants. The mutations were directed to a region of the T-antigen gene, 0.5 map units, that is thought to be important for interaction of the protein with the viral origin of DNA replication. Of t...

We present a detailed first-principles analysis of the (001) surface methylammonium lead triiodide (MAPbI3). With density functional theory, we investigate atomic and electronic structure tetragonal (I4cm) phase MAPbI3. analyzed models with MAI-termination (MAI-T) PbI2-termination (PbI2-T). For both terminations, studied clean series reconstructions. find that MAI-T model is more stable than it...

The model consists of units that represent the firing rate V of entire neural populations. We assume the inputs to a population have Gaussian white noise added to them (Wiener process W ), which models the input variability introduced by stochastic spike-generation in the input populations, and is weighted by a factor c. V (t) can thus be interpreted as the dynamic rate parameter of a nonhomoge...