The compressional characteristics and tableting properties of starches from four yam species namely Dioscorea dumetorum Pax (Bitter); Dioscorea oppositifolia L (Chinese); Dioscorea alata L.DIAL2 (Water) and Dioscorea rotundata Poir (White) were investigated in comparison with corn starch. The physicochemical properties of the starches were evaluated using established methods while the compressi...

This work investigated the technical feasibility of preparing, stabilizing and isolating poorly water-soluble drug nanoparticles via a small-scale antisolvent precipitation process operating in semi-continuous mode. Specifically, novel was demonstrated for carrier particle mediated production, stabilization isolation valsartan into solid form using montmorillonite clay particles as carrier. The...

The practice of multifunctional excipients is gaining more and attention as it simplifies the process drug formulation by substituting necessity using mixture many excipients. are class which includes pre-–processed co-processed provides added functionalities to formulation. Functionality an excipient a useful property helps in manufacturing improves quality well applicability material. Researc...

The purpose of this study is to optimize the composition extragranular excipients (EGE) and mixing time granules with EGE paracetamol tablet formulation using Design Experiments (DoE) approach. effect on granule tableting properties was investigated a combined model mixture process factors (Design-Expert 12). A total 18 formulations were manufactured by wet granulation varying compositions time...