Cisplatin (cis-diamminedichloroplatinum (II) or CDDP), used in the treatment of many solid-tissue cancers, has its chief side-effect in nephrotoxicity. Hence, this study sought to investigate and compare the protective effect of gallic acid (GA) and tannic acid (TA) against cisplatin induced nephrotoxicity in rats. The rats were given a prophylactic treatment of GA and TA orally at a dose of 20...

The details of the technique were given previously (Carson and Frisch, 1953) and consisted of the inoculation of standard amounts of influenza A virus (PR8 strain) into the allantoic cavity of 10 day old chick embryos. Thirty minutes later one to two mg of neutralized and filtered tannic acid were introduced and the fluids were harvested, tested for hemagglutination and for infectivity after st...

A tannin isolated from Paullinia pinnata Linn., and tannic acid, have cardiotonic actions on the isolated perfused frog heart. Paullinia tannin is more firmly "fixed" than tannic acid. Tannin solutions contain peroxide, but the cardiotonic action is not dependent on this, since drugs believed to prevent peroxide formation, and sodium pyruvate which destroys peroxides, do not prevent the cardiot...

An elevated titer of anti-aorta antibodies was detected with a significantly higher frequency in cases of aortitis syndrome than in those of other diseases by the complement fixation test and tannic acid hemagglutination test. This finding indicates participation of immune mechanism in the development of aortitis syndrome. The direct fluorescent antibody technique disclosed that aorta antigens ...

Production of tannase by Aspergillus flavus (MTCC 3783) using tamarind seed powder as substrate was studied in submerged fermentation. Plackett-Burman design was applied for the screening of 12 medium nutrients. From the results, the significant nutrients were identified as tannic acid, magnesium sulfate, ferrous sulfate and ammonium sulfate. Further the optimization of process parameters was c...