نتایج جستجو برای: tap1
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(f) Explicitly verify that the the 5 global sections above generate the invertible sheaf OP2(2)|X(−C) at every point of X. Therefore there is a unique morphism φ : X → P such that φOP4(1) equals OP2(2)|X(−C) and the pullback of the homogeneous coordinates are the 5 sections above. (g) Also verify that y0, y1, y2, y3 are identically zero on the line L. Therefore φ contracts L to the point p = [0...
The Kazakh population in Xinjiang Province in northwestern China exhibits a high incidence of esophageal squamous cell carcinoma (ESCC). Although the etiology of esophageal carcinoma (EC) has not been elucidated, there are reports of the involvement of an immunologic mechanism. In the current study, 268 Kazakh ESCC patients and 500 age- and sex-matched control subjects were recruited. DNA was e...
Association of LMP/TAP Gene Polymorphisms with Tuberculosis Susceptibility in Li Population in China
BACKGROUND Tuberculosis (TB) is a contagious disease affected by multiple genetic and environmental factors. Several association studies have suggested that cellular immune response is vital for controlling and preventing of tuberculosis infection. Low molecular weight polypeptides (LMPs) and transporters with antigen processing (TAPs) are the main molecules in the processing and presentation p...
Serous ovarian cancer is the most common and primary death type in cancer. In recent studies, tumor microenvironment immune infiltration significantly affect prognosis of This study analyzed four gene expression types TCGA database to extract differentially expressed genes verify prognostic significance. Meanwhile, functional enrichment protein interaction network analysis exposed that these we...
PURPOSE Malignant epithelial ovarian cancer effusions are important in disease dissemination and clinical outcome. The identification of biochemical events active in effusions may improve our identification and application of targeted therapeutics. EXPERIMENTAL DESIGN Archival effusion samples for which outcome information was known were studied. Clinical variables were comparable between the...
A clinician’s attention is normally drawn to a system only when it malfunctions. The HLA system is no exception in this regard, but in contrast to other systems, it also arouses interest when it functions well — too well, in fact. The most dramatic malfunction of the HLA system occurs when its genes falter in their expression, resulting in HLA class I or class II deficiencies (the bare lymphocy...
The antigenic repertoire presented by MHC molecules is generated by the antigen processing and presentation (APP) pathway. We analyzed the evolutionary history of 45 genes involved in APP at the inter- and intra-species level. Results showed that 11 genes evolved adaptively in mammals. Several positively selected sites involve positions of fundamental importance to the protein function (e.g. th...
Localization, Expression Change in PRRSV Infection and Association Analysis of the Porcine TAP1 Gene
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