Chemotherapy-induced taste disorder is one of the critical issues in cancer therapy. Bortezomib, a proteasome inhibitor, is a key agent in multiple myeloma therapy, but it induces a taste disorder. In this study, we investigated the characteristics of bortezomib-induced taste disorder and the underlying mechanism in mice. Among the five basic tastes, the sour taste sensitivity of mice was signi...

In the daily language the word " taste " refers to the sensations that professionals carefully distinguish as taste and odour, or flavour. The sense of taste is notably robust with age, whereas declines in the sense of olfaction are dramatic. Age-related changes in taste functioning do not affect all individuals, and some elderly individuals are essentially unimpaired. Age has a more significan...

Introduction: Themajority of patients receiving concurrent chemoradiotherapy frequently complain of changes in their taste perception, and other distressing symptoms affecting their quality of life. This study was undertaken to determine the pattern of gustatory impairment and its recovery in irradiated head and neck cancer patients in India.   Materials and Methods: Thirty patients undergoing ...

This paper axiomatizes an intertemporal version of the Smooth Ambiguity decision model developed in Klibanoff, Marinacci, and Mukerji (2005). A key feature of the model is that it achieves a separation between ambiguity, identified as a characteristic of the decision maker’s subjective beliefs, and ambiguity attitude, a characteristic of the decision maker’s tastes. In applications one may thus...

This paper presents a general equilibrium model in which middlemen emerge to facilitate trade in an environment of idiosyncratic tastes and heterogeneous goods. The gains to the traders can be measured along three dimensions: the rate of production, the time preference losses generated by the matching process, and the quality of the match between consumers’ preferences and the goods they ultima...

This paper is an essay on the challenges that arise when attempting to quantify the extent of labor market discrimination against women. Three major economic theories of labor market discrimination are discussed: tastes and preferences, market power, and statistical discrimination. Decomposition methodology is presented and critiqued. Issues associated with attempts to use decomposition methodo...

PURPOSE OF REVIEW A sensitive period in development is one in which it is easier for learning to take place; the behaviour can however still be learned at a later stage, but with more difficulty. This is in contrast to a critical period, a time at which a behaviour must be learned, and if this window of opportunity is missed, then the behaviour can never be acquired. Both might determine food a...

Welfare economics provides the basis for judging the achievements of markets and policy makers in allocating resources. Its most powerful conceptual tool is the utility possibility frontier. This defines the set of utility allocations that can be achieved in a society subject to the constraints of tastes and technologies. Any allocation on the frontier cannot be Pareto dominated and hence would...

This lecture address the following two key criticisms of the empirical application of revealed preference theory: When the RP conditions do not reject, they do not provide precise predictions; and when they do reject, they do not help characterize the nature of irrationality or the degree/direction of changing tastes. Recent developments in the application of RP theory are shown to have rendere...

Taste perception depends not only on the chemical and physical properties of tastants, but may also depend on the physiological and psychological conditions of those who do the tasting. In this study, the effects of mood state on taste sensitivity was evaluated in humans who were exposed to conditions of mental or physical fatigue and tension. Taste responses to quinine sulfate (bitter), citric...