BACKGROUND suPAR, the soluble form of the urokinase-type plasminogen activator receptor, has been identified as a biomarker of infection in adults but its properties in neonatal infection are not known. METHODS Plasma suPAR levels were determined by ELISA in 47 term neonates with infection (19 bacterial and 28 viral) and in 18 healthy neonates as controls. Thirteen out of 47 infected neonates...

OBJECTIVE To compare the characteristics of neonatal seizures between preterm and full-term infants in intensive care unit. METHOD A prospective study was developed with 104 high-risk newborn, 30 preterm and 74 full-term infants, with clinical seizures. The dependent variable was gestational age. STATISTICAL ANALYSES Fisher's exact test, odds-ratio and Mann Whitney U test. RESULTS There w...

Medical advancements in neonatology have significantly increased the number of high-risk preterm survivors. However, recent long-term follow-up studies have suggested that preterm infants are at risk for behavioral, educational, and emotional problems. Although clear relationships have been demonstrated between preterm infants and developmental problems during childhood and adolescence, less is...

AIM To investigate the pharmacokinetics and pharmacodynamics of single dose propacetamol in preterm and term infants on the first day of life. METHODS Neonates were stratified by gestational age. Preterm (< 37 weeks) and term (37-41 weeks) infants received a single dose of propacetamol in the first 24 hours of life when they had minor, painful procedures or as additional treatment in infants ...

background:extrauterine growth restriction remains a common and serious problem in newborns especially who are small, immature, and critically ill. very low birth weight infants (vlbw) had 97% and 40% growth failure at 36 weeks and 18-22 months post-conceptual age respectively. the postnatal development of premature infants is critically dependent on an adequate nutritional intake that mimics a...

background: hyperbilirubinemiais a common problem in newborn infants. it can progress to kernicterus in severe forms, unless an intervention is initiated. the objective of this study was to compare the efficacy of clofibrate with phenobarbital in full-term neonates with nonhemolytic jaundice. methods: this double blind clinical trial study was performed on 60 neonate who were divided randomly i...

BACKGROUND Automated interleukin assays are promising diagnostic aids for early-onset neonatal sepsis, however, reference values for healthy term neonates are incompletely known. The goal of this study is to determine reference values for interleukin-6 (IL-6) and interleukin-8 (IL-8) in cord blood of healthy term neonates. METHODS AND FINDINGS Women were recruited from April 2012 to August 20...

AIM This study aimed to compare Neonatal Pain, Agitation, and Sedation Scale (N-PASS) with Premature Infant Pain Profile (PIPP) for the assessment of acute prolonged pain in ventilated neonates. METHODS This study was conducted in two phases. In phase 1 of the study, we assessed whether neonates on assisted ventilation experienced acute prolonged pain. In phase 2, the aim was to compare N-PAS...

INTRODUCTION To identify and assess the characteristics, risk and outcome of neonates treated with empiric antibiotics for suspected early onset sepsis (EOS). MATERIAL AND METHODS This is a retrospective study conducted at a Malaysian government hospital. Records of neonatal patients admitted within 72 h of life and prescribed with empirical antibiotic therapy for suspected EOS were reviewed....