Abstract Background A toxin produced by Clostridium tetani causes an acute illness called tetanus. Although there are still isolated incidences of the disease in emerging nations with social and economic squalor, number cases has dropped as a result vaccination. This case report intends to describe physical therapy treatments given two patients at Federal Medical Center Abeokuta who were diagno...

Vaccinations are recommended throughout life to prevent vaccine-preventable diseases and their sequelae. Adult vaccination coverage, however, remains low for most routinely recommended vaccines and below Healthy People 2020 targets. In October 2014, the Advisory Committee on Immunization Practices (ACIP) approved the adult immunization schedule for 2015. With the exception of influenza vaccinat...

Tetanus is an acute severe disease induced by an exotoxin, often lethal. All cases occur in untreated or inadequately vaccinated patients and mainly in elderly patients who accumulate many risk factors. The current management of wounds faced difficulties in the assessment of immunization status and wound risks status. Indeed, all injuries can potentially lead to tetanus. Minor risks and chronic...

The effect of abatacept, a selective T-cell co-stimulation modulator, on vaccination has not been previously investigated. In this open-label, single-dose, randomized, parallel-group, controlled study, the effect of a single 750 mg infusion of abatacept on the antibody response to the intramuscular tetanus toxoid vaccine (primarily a memory response to a T-cell-dependent peptide antigen) and th...

HIV-exposed but uninfected (HEU) infants born to HIV-infected mothers from areas in the world with a high burden of infectious disease suffer higher infectious morbidity and mortality than their HIV unexposed uninfected (HUU) peers. Vaccination provides protection from infection. The possibility exists that altered response to vaccination contributes to the higher rate of infection in HEU than ...

Since a nationwide childhood vaccination with tetanus toxoid, tetanus has become a rare disease in Korea. However, we recently experienced 17 cases of adult tetanus in a university hospital during a 21-month period. Seventy percent of the patients were female, and the mean age was 63 yr (range, 29-87). The majority (88.2%) of the patients did not get primary vaccinations for tetanus and decenni...

Transplacentally transferred antibodies induced by maternal pertussis vaccination interfere with infant immune responses to primary vaccination. We evaluated whether this interference remains in toddlers after booster In a prior phase IV, observer-blind, placebo-controlled, randomized study (NCT02377349), pregnant women Australia, Canada and Europe received intramuscular tetanus-reduced-antigen...

OBJECTIVE To prospectively evaluate the impact of parental satisfaction on childhood immunization and the mediating role of age-appropriate well-child care. DESIGN Secondary analyses of cohort data from the National Evaluation of Healthy Steps for Young Children. Data sources included an enrollment questionnaire, parent interview at 2 to 4 months, and medical records. SETTING Twenty-four pe...

Different subtypes of vasculitis have been reported after vaccination in adults. However, only one case of Kawasaki disease in an infant after hepatitis B vaccination has been described. We report a case of Kawasaki disease in a 2 month-old infant who developed the Kawasaki disease 1 day after receiving his first dose of diphtheria tetanus-acellular pertussis, Haemophilus b and pneumococcal con...

OBJECTIVE To evaluate public knowledge regarding predisposing factors, fatality and prevention of Tetanus and Rabies and attitudes toward vaccination and post-exposure prophylaxis. METHODS A population-based, cross-sectional survey was conducted in all the 18 towns of Karachi, the largest metropolitan city of Pakistan, from December 2007 to January 2008. Men and women of more than 18 years of...