In 65 patients with a previous transmural myocardial infarction (anterior in 33, inferior in 32), exercise thallium scanning was compared with 12-lead exercise electrocardiography to see if multivessel disease could be detected. At coronary arteriography 40 patients were shown to have multivessel disease ( greater than or equal to 70% diameter stenosis in two or three vessels) and 25 patients h...

hantzsch 1, 4-dihydropyridines (1,4-dhps) can be oxidized to the corresponding pyridine derivatives by thallium triacetate in high yields.

Viable, chronically dysfunctional myocardium with reduced resting flow (or hibernating myocardium) is an important prognostic factor in ischemic heart disease. Although thallium-201 imaging is frequently used to assess myocardial viability in patients with ischemic cardiomyopathy, there are limited data regarding its deposition in hibernating myocardium, and this data suggest that thallium rete...

We extended the quantitative seven-pinhole method to follow the dynamics of thallium redistribution after exercise. We observed a pattern of slow late thallium clearance that appears to be characteristic of myocardium supplied by obstructed coronary arteries. In 28 subjects, quantitative thallium scintigrams (seven-pinhole tomography, circumferential count profiles) and blood samples for thalli...

OBJECTIVES Thallium-201 is efficient for myocardial perfusion imaging, but leads to relatively high radiation exposure in patients. The purpose of this study was to compare the efficiency of low-dose thallium-201 imaging with cadmium-zinc-telluride (CZT) cameras with regular-dose thallium-201 imaging with conventional cameras. METHODS We prospectively studied 137 consecutive patients referred...

OBJECTIVES The aim of this study was to determine which clinical, exercise and thallium variables can aid in the identification of three-vessel or left main coronary artery disease (3VLMD) in patients with one abnormal coronary territory (either a reversible or fixed defect) on exercise thallium testing and to test the prognostic value of these variables. BACKGROUND Although the sensitivity o...

The goal of this study was to determine the prognostic utility of the exercise thallium-201 stress test in ambulatory patients with chest pain who were also referred for cardiac catheterization. Accordingly, 4 to 8 year (mean +/- 1SD, 4.6 +/- 2.6 years) follow-up data were obtained for all but one of 383 patients who underwent both exercise thallium-201 stress testing and cardiac catheterizatio...

A 40-year-old woman was admitted to the hospital with painful paresthesias after drinking brandy and red wine containing thallium. A severe acute axonal sensorimotor neuropathy was diagnosed. She rapidly deteriorated and became comatose within less than a week.1 Metallic skin discoloration and darkening of the cheek and chin areas was observed (figure). Two weeks after thallium ingestion patchy...

We compared the effects of symptom-limited upright and supine exercise on 201Tl distribution and kinetics in the heart and lungs of 100 consecutive patients. Our analysis was based on data obtained with a digital gamma camera in the 45 degrees left anterior oblique position at 5, 40, 240, and 275 min postadministration of [201Tl]chloride. We found significant differences in the results at the 5...

27. Skulskii A, Manninen V, Jarnfelt J: Interaction of thallous scans with the cation transport mechanism of erythrocytes. Biochim Biophys Acta 298: 702, 1973 28. L'Abbate A, Biagini A, Michelassi C, Maseri A: Myocardial kinetics of thallium and potassium in man. Circulation 60: 776, 1979 29. Leppo JA, Okada RD, Guerrero JL, Strauss HW, Pohost GM: The relationship of coronary flow to Tl-201 red...