The title compound, C23H21N3O2, is constructed about an almost planar disubstituted amino-urea residue (r.m.s. deviation = 0.0201 Å), which features an intra-molecular amine-N-H⋯N(imine) hydrogen bond. In the 'all-trans' chain connecting this to the terminal meth-oxy-benzene residue, the conformation about each of the imine and ethyl-ene double bonds is E. In the crystal, amide-N-H⋯O(carbon-yl)...

Chiral polyborate based Brønsted acids prepared from the VANOL and VAPOL ligands are known to catalyze the reaction of diarylmethyl imines with diazoesters to give cis-aziridines. In the present work, this same catalyst is shown to catalyze the reaction of the same imines with diazoacetamides to give trans-aziridines with the same high asymmetric inductions as seen with cis-aziridines, enabling...

The title chiral imine, C(17)H(15)NS, has been obtained via a direct synthesis route. The imine group displays the common E configuration, and is almost coplanar with the thio-phene heterocycle; the dihedral angle between the C=N-C group and the thio-phene ring is 5.1 (8)°. In contrast, the naphthyl group makes an angle of 83.79 (13)° with the thio-phene ring. The observed solid-state mol-ecula...

3,4-Dihydro-2H,6H-pyrimido[1,2-c][1,3]benzothiazin-6-imine (PD 404182) is a virucidal heterocyclic compound active against various viruses, including HCV, HIV, and simian immunodeficiency virus. Using facile synthetic approaches that we developed for the synthesis of pyrimido[1,2-c][1,3]benzothiazin-6-imines and related tricyclic derivatives, the parallel structural optimizations of the central...

In this study, a series of 4-(3-benzylbenzo[ d]thiazol-2(3 H)-ylidene)-cyclohexa-2,5-dien-1-one derivatives are efficiently synthesized in excellent yields by reactions 2-chlorobenzothiazole, benzyl bromides, and phenols acetonitrile under reflux catalyst-free conditions the presence triethylamine for 2 h. The structures products characterized NMR, IR, EI-MS, elemental analyses.

The title compounds, (4-trifluoromethoxyphenyl)-2,5-dimethyl-3-(2-R-thiazol-4-yl)-1H-pyrroles, were prepared in four steps starting from commercially available 4-trifluoromethoxyaniline. The pyrrole (second ring) was added in one step using the Paal-Knorr method. The thiazole (third ring) was added in three steps using chloroacylation with chloroacetonitrile followed by heterocyclization with t...

Cycloaddition of pyridine N-imine with 6-alkyl-4-oxohex-5-ynoates followed by condensation with hydrazine provides concise access to pharmacologically active 6-(pyrazolo[1,5-a]pyridin-3-yl)pyridazinones. For the first time alkynyl heterocycles are also shown to be effective dipolarophiles for pyridine N-imine, and analogous compounds can be accessed directly in modest yields through the reactio...

crystal. a) Preparation of porous network complex [(ZnI2)3(1)2(2a)]n. b) Single-crystal-to-single-crystal transformation of 2a into labile imine 3a in the pore of the network complex. c) Crystal structures before and after crystalline-state reaction. NW2/2006G284 Direct Observation of the Labile Imine Formation through Single-crystal-tosingle-crystal Reactions in the Pores of a Porous Coordinat...

In the title compound, C(15)H(15)NO(2), the phenol group make dihedral angles of 2.4 (2) and 24.1 (9)° with the imine linkage (-C=N-) and the phenyl group, respectively, and the mol-ecule adopts the enol-imine tautomeric form, so the mol-ecular structure is stabilized by a strong intra-molecular O-H⋯N hydrogen bond. The crystal structure features a weak C-H⋯π inter-action.

The title compound, C(33)H(30)N(2), has an E configuration at the imine double bond. The angle between the least-squares planes of the imine C=N-C group and the benzene ring of the 2,4,6-trimethylphenyl substituent is 85.38 (11)°. The crystal structure is sustained mainly by inter-molecular π-π inter-actions (3.510 Å) between the two fluorene rings and some C-H⋯π inter-actions.