Abstract The paper presents a method of the preparation and functionalization polymer microspheres consisting glycidyl methacrylate (GMA) crosslinking agents: 1,4-dimethacryloyloxybenzene (1,4DMB) trimethylolpropane trimethacrylate (TRIM). Poly(GMA- co -1,4DMB) poly(GMA- -TRIM) were obtained by seed swelling polymerization. To introduce thiol groups into structure, reaction with thiocarboxylic ...

background & aim: parkinson's disease (pd) can be created with loss of dopaminergic substantial nigra neurons which is widely associated with oxidative stress and reduced glutathione (gsh), as the most important and abundant thiol in tissues and one of the antioxidant defense, is one of the earliest biochemical events related to parkinson's and consumption of antioxidants has a protec...

Brightly luminescent, atomically precise subnanometer clusters of silver protected by glutathione were covalently functionalized by solution phase thiolated graphene using ligand exchange. A hybrid molecule was formed, which was obtained in a nearly pure form by phase transfer from the aqueous to the organic phase. The resulting hybrid exhibited properties of both of these nanoscale materials. ...

pegylation is a well-established technique utilized to overcome the problems related to the therapeutic applications of peptides and proteins. reasons for the pegylation of these biological macromolecules include reducing immunogenicity, proteolytic degradation and rapid clearance from blood circulation. octreotide is an octapeptide analogue of naturally-occurred somatostatin. this peptide has ...

background & aim: parkinson's disease (pd) can be created with loss of dopaminergic substantial nigra neurons which is widely associated with oxidative stress and reduced glutathione (gsh), as the most important and abundant thiol in tissues and one of the antioxidant defense, is one of the earliest biochemical events related to parkinson's and consumption of antioxidants has a protective e...

in this study the effects of fe2o3 and fe3o4 magnetic nanoparticles and edta on urease activity was investigated. the effect of nano-fe2o3 and nano-fe3o4 on urease activity were investigated. urease activity was studies by uv-vis spectrophotometry at 40 °c at ph = 7.2 using sodium phosphate as buffer. measurements were carried out using 0.075 mg/ml of urease and a range of nano-fe2o3 and nano-f...

The development of simple and efficient crosslinking techniques is sought after for a variety of applications including bioconjugation, material synthesis and design, and surface functionalization. The use of ‘‘Click’’ reactions is becoming increasingly popular because it offers excellent coupling efficiency and is applicable to many synthetic situations. One of the most popular methods is the ...

Various types of fluorescent carbon nanoparticles, often called dots (CDs), are synthesized by different polycondensation methods: microwave irradiation, hydrothermal conditions or solution chemistry at ambient temperature with subsequent chemical functionalization. The CDs deposited on TiO2 films to be probed as electron transport layers in perovskite photovoltaics and the anode for photoelect...

Gold nanoparticles (AuNPs) are widely used in biomedical diagnostics due to their unique plasmonic properties, with larger AuNPs showing higher extinction coefficients for the plasmon band and, consequently, more intense colors than commonly spherical 20 nm AuNPs. Other factors can be important performance of different-sized AuNPs, including surface area, colloidal stability, and curvature effe...