Reaction of readily available 2-formyl -1-methyl-5-nitroimidazole (1) with 4-substituted-2-hydrazinothiazoles (2) afforded 2-formyl-l-methyl-5- nitroimidazole 4-substituted -2- thiazolylhydrazones (3). Reaction of thiochromitn-4-one (4) with thiosemicarbazide gave thiochroman-4- one thiosemicarbazone (5). Reaction of compound 5 with clc- haloaldehyde or ketones y ielded thiochroman--#-one ...

I. Blood Pressure Responses to Epinephrine in Dogs with Certain Humoral Backgrounds. Gale C. Boxill and Robert V. Brown 1 II. Isobols of Dose-Effect Relations in the Combination of Nikethamide (Coramine) and Phenobarbital. S. Loewe 6 III. Detoxication and Excretion of Mephentermine. Sidney S. Walkenstein, Nina Chumakow and Joseph Seifter 16 IV. The Effects of Analgesic Agents on Barbiturate Res...

Metal complexes were prepared by the reaction of thiosemicarbazone with CuCl2, NiCl2, CoCl2, Cu(OAc)2, Ni(OAc)2, and Co(OAc)2. The thiosemicarbazone coordinates to metal through the thionic sulfur and the azomethine nitrogen. The thiosemicarbazone was obtained by the thiosemicarbazide with 3-acetyl-2,5-dimethylthiophene. The identities of these compounds were elucidated by IR, (1)H, (13)C-NMR, ...

We have been interested for some time in thiosemicarbazide derivatives of periodate-oxidized polysaccharides many of which show considerable activity against Sarcoma 180 (S-180) in the mouse (2). The antitumor activity and toxicity of these deriva tives are completely reversed if pyridoxine (B6) is administered at the same time. We were led to investigate glyoxal and methylglyoxal bisthiosemica...

CuInS2 nanostructures were  synthesized  via  a  simple  surfactant-free solvothermal  route.  In  this  synthesis,  thiosemicarbazide  and thioglycolic acid were used as sulfur sources. The effects of different parameters such as type of precursor and time on the morphology and particle  size  of  the  samples  have  been  investigated.  The nanostructures  were  characterized  by  means ...