PURPOSE To review the recent data about eyelid morphogenesis, and outline a timeline for eyelid development from the very early stages during embryonic life till final maturation of the eyelid late in fetal life. METHODS The authors extensively review major studies detailing human embryologic and fetal eyelid morphogenesis. These studies span almost a century and include some more recent cada...

Eyelid lacerations are common in horses and should be regarded as surgical emergencies to prevent undesirable tissue devitalization, infection, scarring, corneal desiccation, and corneal ulceration. Lacerations usually can be repaired in the standing, heavily sedated horse. General anesthesia may be required when there is extensive trauma or with an unruly horse. Even when horses are not evalua...

Patients with facial paralysis may develop ophthalmic complications. Poor eyelid closure and lagophthalmos place the patient at increased risk for the development of corneal problems such as epithelial defects, stromal thinning, bacterial infection, and even perforation. Initial treatment should be conservative and include the use of ocular lubricants, moisture chambers, and taping of the lower...

PURPOSE Embryonic eyelid closure is a well-documented morphogenetic episode in mammalian eye development. Detection of eyelid closure defect in humans is a major challenge because eyelid closure and reopen occur entirely in utero. As a consequence, congenital eye defects that are associated with failure of embryonic eyelid closure remain unknown. To fill the gap, we developed a mouse model of d...

Transcutaneous lower blepharoplasty addresses excess skin, muscle, and fat through an infraciliary cutaneous incision. This approach offers excellent exposure to the fat pads; however, violation of the orbital septum may result in postoperative lower eyelid retraction, with resultant aesthetic disfigurement as well as exposure keratoconjunctivitis.1 The transconjunctival approach to lower bleph...

OBJECTIVE We describe the case of a patient with metastatic breast cancer who presented with eyelid margin thickening and madarosis more suggestive of sebaceous cell carcinoma than metastatic disease. Histopathology confirmed metastatic breast adenocarcinoma. CASE REPORT A 59-year-old woman with a known history of metastatic breast carcinoma actively enrolled in a clinical trial presented wit...

PURPOSE To report the frequency and relationship of eyelid retraction, lid lag, lagophthalmos, and von Graefe's sign in a group of patients with Graves' ophthalmopathy and compare these findings to those in a group of normal individuals. DESIGN Retrospective comparative cohort study. PARTICIPANTS Fifty consecutive Graves' ophthalmopathy patients were compared to a control group of 50 normal...

BACKGROUND Double-eyelid procedure to construct a supratarsal fold is the most common aesthetic surgery in young Asian adults. More complex surgical procedures, such as fat grafting or filler injection, are often indicated during traditional, long-incision, double-eyelid procedures to achieve better aesthetic results for patients with hollowness of the upper eyelids. OBJECTIVES The authors so...

© 2014 Canadian Medical Association or its licensors CMAJ 1 A 52-year-old man presented with redness and irritation of the left eye. He had tried using artificial tear drops and gels without much benefit. On examination, the patient had redundant, wrinkled eyelid skin bilaterally with a greater amount on the affected side (Figure 1A). Ptosis of the left upper eyelid was evident, and the upper e...

PURPOSE To determine whether taping of the lower eyelid laterally and upward onto the temple region (to mimic a lateral tarsal strip procedure) can effectively predict whether lateral tarsal strip surgery will lead to resolution or improvement in functional epiphora by correcting eyelid laxity. METHODS A case series of 28 eyes in 20 patients with symptomatic epiphora and equivocal lateral eye...