OBJECTIVE The aim of this study was to investigate whether terrestrosin D (TED) inhibits the progression of castration-resistant prostate cancer and consider its mechanism. METHODS Cell cycle, mitochondrial membrane potential (ΔΨm) and apoptosis were determined by flow cytometry. Caspase-3 activity and vascular endothelial growth factor secretion were detected by a caspase-3 assay and human v...

Purpose To radiologically examine for the presence of bony remodeling of the orbit in thyroid eye disease (TED). Methods Computed tomography (CT) scans of 248 orbits of 124 patients with TED and 185 orbits of 138 controls were retrospectively reviewed, and the following parameters measured: the angle of the inferomedial orbital strut (AIOS), the angle of the medial wall (AMW), and the diamete...

TED is a program that “invents” conceptual schematics of optimized thermal systems. TED is based on the view that innovative design can be modeled as a search process and uses elements of the search algorithms that originated in the field of Artificial Intelligence. The search is guided by a special form of exergetic analysis. The theory behind the TED is discussed in details elsewhere. This pa...

Without intervention, it has been found that surface-initiated photoiniferter-mediated photopolymerization (SI-PMP) of methyl methacrylate suffers from irreversible termination, which leads to cessation of polymerization. These irreversible termination reactions were successfully reduced by preaddition of tetraethylthiuram disulfide (TED). The poly(methyl methacrylate) layers were also reinitia...

STUDY DESIGN This study analyzed the effects of autografted nucleus pulposus on nerve root axon morphology, neurophysiologic function, and sodium channel expression. OBJECTIVES To investigate the chronic effects of the epidural implantation of nucleus pulposus on nerve root morphology, neural activity, ectopic discharge, mechanosensitivity, and sodium channel expression. SUMMARY OF BACKGROU...