نتایج جستجو برای: thymocyte
تعداد نتایج: 6432 فیلتر نتایج به سال:
Mice Differences between Men and −− Potential Developmental δ γ Expression, and β TCR TCR Gene Rearrangements, Intracellular Thymocyte Development: δ γ and β α Human
We demonstrated that interleukin 1 (IL-1), a potent peptide mediator in immune and inflammatory responses, stimulates the synthesis of cAMP in a variety of IL-1-responsive cell targets. We also showed that cAMP analogs and cAMP-inducing agents can replace IL-1 in the induction of interleukin 2 receptors on lymphocytes as well as in phytohemagglutinin-induced murine thymocyte proliferation. By u...
Immune dysregulation is a mechanism contributing to ineffective hematopoiesis in a subset of myelodysplastic syndrome patients. We report the first US multicenter non-randomized, phase II trial examining the efficacy of rabbit(r)-anti-thymocyte globulin using 2.5 mg/kg/day administered daily for 4 doses. The primary end point was hematologic response; secondary end points included duration of r...
When mature thymus-derived (T) lymphocytes from peripheral lymphoid organs are activated by antigen or mitogen, an increase in the expression of the surface receptor for interleukin 2 (IL-2-R) is observed that precedes the development of effector function (1-3). While IL-2 is known to be a specific growth factor for such mature T cells (4, 5), it is not known whether IL-2 is also involved as a ...
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