BACKGROUND Ovarian cysts are a common cause for gynecological surgery. However, some cysts are a direct result of endocrine disorders and do not require surgery. This report describes an unusual case in which persistent ovarian cysts are associated with primary hypothyroidism in a young woman. The data were collected by history-taking, physical examination, laboratory tests, ultrasound, magneti...

To investigate the relationship between thyroid function and carotid intima-media thickness (CIMT) in a relatively large general population with euthyroid status we initially enrolled 1772 Japanese adults (421 men and 1351 women) who participated in a medical screening program for the general population over 40 years old. To evaluate only euthyroid subjects without vascular diseases and/or its ...

Graves’ Disease (GD) is the most common form of hyperthyroidism. It affects 3% female patients and 0.5% male usually between age 30-60. cause 80% hyperthyroid cases in USA. The pathogenesis disease complex autoimmunity plays a key role. antibodies stimulating thyrotropin receptor (TRAb) lead to uncontrolled Thyroid-stimulating Hormone (TSH) overproduction thyroid hormones from overactive gland....

Khosrow Adeli Clinical Biochemistry, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, M5G 1X8 Canada List of abbreviations: CALIPER, Canadian Laboratory Initiative on Pediatric Reference Intervals; RIDL, Reference Intervals and Decision Limits; IFCC, International Federation of Clinical Chemistry and Laboratory Medicine; CLSI, Clinical Laboratory Standards Institute; GGT...

OBJECTIVE Aneurysmal subarachnoid hemorrhage puts patients at high risk for the development of pituitary insufficiency. We evaluated the incidence of pituitary dysfunction in these patients and its correlation with clinical outcome. METHODS Pituitary function was tested in 66 consecutive patients in the first 15 days after aneurysmal subarachnoid hemorrhage. The following were measured in all...

This review focuses on recent advances in the structure-function relationships of thyroid-stimulating hormone (TSH) and its receptor. TSH is a member of the glycoprotein hormone family constituting a subset of the cystine-knot growth factor superfamily. TSH is produced by the pituitary thyrotrophs and released to the circulation in a pulsatile manner. It stimulates thyroid functions using speci...

Abstract. A case of a female, 10-year-old rhesus macaque (Macaca mulatta) with spontaneous chronic lymphocytic thyroiditis is presented. At necropsy, the thyroid gland was slightly enlarged, up to 2 mm large, round, confluent, beige foci on surface both lobes. Histopathologic features resembled human Hashimoto's thyroiditis: multifocally, interstitium infiltrated by lymphocytes and variably siz...

Thyroid hormones physiologically regulate the semen quality, by altering testosterone concentrations, and different seminal parameters, as well sperm motility, viability volume. Serum thyroxine (T4), free (fT4), thyroid-stimulating hormone (TSH) (T) concentrations were measured in 26 adult Labrador Retriever dogs (n. 20 normospermic n. 6 azoospermic groups), aged 3 ± 0.5 years old, to determine...