BACKGROUND Thyroid lymphoma is rare, with no standard therapeutic protocol. Radiotherapy is often employed. PATIENTS AND METHODS Nine patients who had received radiotherapy for thyroid lymphoma in our Institute, from September 2005 to August 2013, were reviewed for hypothyroidism. The median radiation dose was 40 Gy. Thyroid-stimulating hormone (TSH) levels were measured before and after radi...

UNLABELLED To assess whether the patient preparation procedure for (131)I scintigraphy could be streamlined, we evaluated the time course of thyroid-stimulating hormone (TSH) elevation after total thyroidectomy or after discontinuation of thyroxine (T(4)) in patients with thyroid cancer. METHODS The clinical records of 284 patients with well-differentiated thyroid cancer were reviewed. All pa...

The activity of the thyroid gland is predominantly regulated by the concentration of the pituitary glycoprotein hormone, thyroid-stimulating hormone (TSH). In the absence of pituitary or of thyrotroph function hypothyroidism ensues. Thus, regulation of thyroid function in normal individuals is to a large extent determined by the factors which regulate the synthesis and secretion of TSH. Those f...

Basal thyroid-stimulating hormone (TSH) and thyroid hormone levels were evaluated in 18 women with bulimia nervosa during a period of active binging and vomiting and again after 7 weeks of abstinence from these behaviors and compared to measures in 27 control women. In 10 of the patients and 11 of the controls, the TSH nocturnal surge was calculated from hourly TSH measurements obtained in the ...

Introduction: Thyroid stimulating hormone (TSH) regulates the level of thyroid hormones synthesized in the thyroid gland. Its measurement greatly facilitates the clinical diagnosis as well as management of pituitary-thyroid diseases. The level of analytes in biological sample is affected by pre-analytical, analytical and post-analytical factors. Objective: To fi nd the effect of delay separatio...

Formaldehyde (HCHO) exposure in industry causes health impairment, especially immune profile. Male albino rats when exposed to HCHO at 5, 10, 15 mg/kg day for 30 days showed decrease in thyroid weight in 10, 15 mg/kg/day HCHO fed group with commensurate follicular regression (epithelial cells), decreased triiodothyronine (T3), thyroxin (T4) deficiency and enhanced thyroid stimulating hormone (T...

INTRODUCTION Radioactive iodine ((131)I) is widely prescribed for treatment of Graves' disease. A dose of 370 to 555 MBq (10 to 15 mCi) is usually enough, but reports of improved remission rates with single doses up to 20-30 mCi, and 38.5 mCi at most, exist. CASE PRESENTATION A 53-year-old male patient was evaluated in September 2005, with symptoms of thyrotoxicosis for 2 years. He presented ...

OBJECTIVE To examine the relation between baseline measurements of thyroid function and response to selective serotonin reuptake inhibitors (SSRIs) and to consider the effect of these antidepressants on thyroid hormone levels. METHODS Nineteen subjects with major depression, but without a history of thyroid treatment or lithium treatment, were treated openly with either sertraline or fluoxeti...

The skeleton is a dynamic organ whose structural integrity depends on constant remodeling, controlled by many local and systemic factors. In this issue of Cell, identify thyroid-stimulating hormone (TSH) as an important regulator of this process.

Subclinical hyperthyroidism may be defined as the presence of free thyroxine and tri-iodothyronine levels within the reference range and a reduced serum thyroid stimulating hormone (TSH) level. In this review the prevalence of low TSH in the population and health consequences of subclinical hyperthyroidism, for example, effects on heart and bone mass, are discussed. Guidelines for treatment are...