A study is described on the standardization of the determination of neonatal total bilirubin. A wide variation in results was shown in surveys held in The Netherlands and Germany and the reasons for this variation were sought. The suitability of commercial bilirubin standards and direct reading instruments, widely used in the neonatal field, was tested by comparing all measurements with those o...

An inverse association between serum bilirubin and cardiovascular disease has been shown in numerous retrospective and prospective studies (1–8) as well as in a metaanalysis study (9 ). Schwertner et al. (1 ) first reported that fasting serum bilirubin concentrations are inversely related to coronary artery stenosis in men. Low serum bilirubin concentrations were found to be associated with an ...

The purpose of this study was to determine a typical reference range for the population of athletes. Results of blood tests of 339 athletes (82 women and 257 men, aged 18-37 years) were retrospectively analysed. The subjects were representatives of different sports disciplines. The measurements of total bilirubin (BIT), iron (Fe), alkaline phosphatase (ALP), alanine aminotransferase (ALT) and g...

The activity of y-glutamyltransferase (EC 2.3.2.2) is measured on the DuPont aca by an adaptation of the Szasz procedure ;-y-glutamyl-p-nitroanilide is transferred to glycylglycine, thereby releasing p-nitroaniline, which is measured at 405 nm. I have noticed low glutamyltransfer-ase activity in patients with cholestasis wherealkaline phosphate (EC 3.1.3.1) is increased, total bilirubin> 100 mg...

conclusions according to our study, phototherapy should not be used as prophylactic therapy for all vlbw infants, but rather it should be individualized in order to maintain low bilirubin levels. results the mean bilirubin level on the first day in both groups exhibited no significant difference. the peak serum bilirubin was 7.7 ± 1.4 and 8.5 ± 2.1 mg/dl in the prophylactic and therapeutic grou...

BACKGROUND Neonatal jaundice is the most frequently encountered diagnostic and therapeutic problem in the newborn. In the jaundiced infant, it is thought that the binding capacity of plasma albumin is exceeded, which allows free bilirubin to diffuse into and accumulate within extravascular tissues, such as the central nervous system. Affected newborns may develop kernicterus. The standard metho...

Diabetic nephropathy (DN), which is a major end-organ complication in diabetes, continues to be the most common cause of end-stage renal disease and accounts for .40% of patients on renal replacement therapy (1). Currently available factors that are routinely used in clinical practice to predict and monitor the progression of DN include degree of proteinuria and both glycemic and blood pressure...

Total bilirubin is determined here with a multipoint calibration approach and with use of Standard Reference Material No. 916 bilirubin from the National Bureau of Standards. The bilirubin calibration solutions prepared in solutions of Cohn Fraction V human albumin were stable for at least one year when stored at -80 degrees C. Studies for direct bilirubin analysis show that the serum sample sh...

BACKGROUND Several studies have demonstrated that higher serum bilirubin inhibits the inflammation and proliferation of vascular smooth muscle cells; also there is a relationship between serum bilirubin and cardiovascular disease. However, the relationship between bilirubin and atrial fibrillation (AF) is still unknown. In our study, we compared serum bilirubin, between nonvalvular AF patients ...