AIMS This study was designed to investigate the therapeutic potential of excimer laser for recurrent painful erosions in patients not suited to treatment with penetrating keratoplasty. METHODS Phototherapeutic keratectomy (PTK) with the excimer laser was performed prospectively on a series of 13 eyes of 12 patients with recurrent corneal erosions in connection with bullous keratopathy of vari...

Graves' disease is a self-limiting autoimmune thyroid disorder caused by stimulating antibodies to the thyroid-stimulating hormone receptor. It usually affects middle-aged females in fourth sixth decade of life. distinguished keratopathy, chemosis, proptosis, and eyelid swelling, addition ocular discomfort. A total 3-5% cases present with severe form orbitopathy, which manifests diminution visi...

This paper describes three siblings, the only affected members of the family, with gelatinous drop-like keratopathy. This rare form of primary corneal amyloidosis has been reported almost exclusively in Japanese literature, and to our knowledge this is the first report of the condition seen in the United Kingdom. Clinical and histological details are presented. The nature and possible aetiology...

Background and aims: A complication of sedation and coma is that some patients are unable to maintain effective eyelid closure. These patients present a higher risk of eye complications. However, in the intensive care unit (ICU), treatment is usually focused on the management of organ failures, and eye care becomes a side issue. Early diagnosis and effective treatment will help prevent microbia...

A 20 year-old man presented with redness, severe visual loss and progressive protrusion of a horn-like mass from the palpebral fissure of his left eye (Fig. 1). He reported gradual appearance of a bubbly tissue on the left cornea progressively growing out of the palpebral fissure over the past several months. He had history of ocular trauma with a piece of glass from an exploding vial with unkn...

PURPOSE Neurotrophic keratopathy is a degenerative disease of the corneal epithelium resulting from impaired corneal innervation, possibly leading to perforation. We aimed to assess the efficacy and tolerance of a new matrix therapy agent (RGTA, Cacicol20), mimicking heparan sulfates, for the management of neurotrophic keratopathy. METHODS We carried out an uncontrolled, prospective, single-c...