نتایج جستجو برای: toxicological analysis

تعداد نتایج: 2831338  

2013
Deepa Thakur Jyotsna Mishra

The antibiotic drug 2-amino-1,9-dihydro-9-(2-hydroxyethoxy)methyl)-6H-purin-6-one has been quantitatively and qualitatively analysis by polarographic & amperometric process. Acyclovir give well identified wave in 1.0mkcl at pH5.0±0.2.Co (II)-Acyclovir complex studied in aqueous phase..The IR spectral data on the drug & its Co (II) complex indicate the co-ordination through nitrogen atom of azid...

2011
Kristiane de Cássia Mariotti Fabiano Barreto Gabriela Cristina Schmitt Ivomar Zancanaro Eliane Dallegrave Rodrigo Bustos Singer Mirna Bainy Leal Renata Pereira Limberger

1Laboratory of Analysis and Toxicological Research, Department of Analysis, Faculty of Pharmacy, Federal University of Rio Grande do Sul Toxicology Laboratory, 2National Agricultural Laboratory of Rio Grande do Sul, LANAGRO/RS , 3Toxicology Information Center of Rio Grande do Sul, State Foundation of Production and Research in Health, 4Department of Botany, Federal University of Rio Grande do S...

2015
Valentina Marchesano Alfredo Ambrosone Juergen Bartelmess Federica Strisciante Angela Tino Luis Echegoyen Claudia Tortiglione Silvia Giordani

The toxicological effects of pristine and chemically modified carbon nano-onions (CNOs) on the development of the freshwater polyp Hydra vulgaris were investigated in order to elucidate the ecotoxicological effects of CNOs. Chemical modifications of the CNOs were accomplished by surface functionalization with benzoic acid, pyridine and pyridinium moieties. thermogravimetric analysis (TGA), Four...

Journal: :Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 2010
U Honkalampi-Hämäläinen E L Bradley L Castle I Severin L Dahbi O Dahlman J-C Lhuguenot M A Andersson P Hakulinen D Hoornstra J Mäki-Paakkanen M Salkinoja-Salonen L Turco A Stammati F Zucco A Weber A von Wright

In vitro toxicological tests have been proposed as an approach to complement the chemical safety assessment of food contact materials, particularly those with a complex or unknown chemical composition such as paper and board. Among the concerns raised regarding the applicability of in vitro tests are the effects of interference of the extractables on the outcome of the cytotoxicity and genotoxi...

Journal: :ALTEX 2014
Adip Roy Mohammad A Akbarsha

the Society of toxicology (StOx), India, and Safety and environmental Assurance Centre (SeAC), Unilever, organized a one day symposium on “Novel Strategies for Toxicological Risk Assessments” on September 4, 2013 at Unilever R&D Centre, Bangalore, India. As animal testing for safety assessment of cosmetic ingredients and products is facing a likely ban in India, there is an increasing need to d...

2016
Qamar Uddin Ahmed

Introduction: Leaves of mempelas paya (Tetracera indica) (family: Dilleniaceae) is traditionally used in diabetes management in Malaysia. However, no attempt has ever been made to discover an active principle responsible for its blood glucose lowering effect. Hence, this research deals with the isolation, in vivo antidiabetic and toxicological evaluation of an active principle. Methods: Chemica...

Journal: :Toxicological sciences : an official journal of the Society of Toxicology 2008
Freddy Dardenne Stefan Van Dongen Ingrid Nobels Roel Smolders Wim De Coen Ronny Blust

Over the years, environment and the human population have seen an increasing exposure to both existing and newly developed chemicals. It is generally accepted that at least some of those are toxic, albeit as pure compound or in combination with others. In response to a growing public awareness and scientific data, the new European chemicals legislation (Registration, Evaluation and Authorizatio...

Journal: :Physiological genomics 2009
Min Ok Song Jianying Li Jonathan H Freedman

Copper is an essential trace element; however, at supraphysiological levels, it can be extremely toxic. Microarray data from HepG2 cells exposed to 100, 200, 400, and 600 microM copper for 4, 8, 12 and 24 h were generated and analyzed. Principal components, K-means, and hierarchical clustering, interactome, and pathway mapping analyses indicated that these exposure conditions induce physiologic...

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