BACKGROUND Previous studies have demonstrated a high prevalence of thyroperoxidase antibodies (TPOAb) and autoimmune hypothyroidism in breast cancer (BC). These studies have been performed in BC patients generally 20-30 days after mastectomy. It is known that stress may have an influence on the immune system and a relation between stressful events and the onset or worsening of autoimmune thyroi...

The aim of the present study was to determine the repairing effects of intercellular adhesion molecule (ICAM)-1-expressing mesenchymal stem cells (MSCs) in mice with autoimmune thyroiditis. Following induction of an experimental autoimmune thyroiditis (EAT) model, mice were randomly divided into the following groups (n=10 each): i) Normal control; and experimental groups that were subject to EA...

Introduction: Helicobacter Pylori (HP) is the most common bacteria that causes chronic bacterial infections in humans. We aimed to investigate possible relationship between HP infection and autoimmune thyroid diseases, as well density platelet-to-lymphocyte ratio (PLR) neutrophil-to-lymphocyte (NLR). Methods: A total of 3380 patients who underwent upper gastro intestinal system endoscopy our te...

Breast cancer is considered the most commonly diagnosed tumors. Biomarkers used for diagnosis and treatment of breast are: tissue biomarkers (PR, ER, HER2, Ki-67) serum (CA15-3, CA125, CA27.29, CEA, cytokeratins). ECD metalloproteinases leptin are emerging promising cancer. There a growing need personalized diagnostics based on tumor genome characterization, relying liquid biopsy containing com...

Background. Postpartum thyroiditis (PPT), characterized by transient hyperthyroidism and transient hypothyroidism, occurs in 5–9% of women. It is accompanied by the presence of circulating antithyroid peroxidase antibodies (TPOAb) which have been associated with an increase in depressive symptomatology compared with TPOAbnegative women. Aim. To assess the frequency and nature of the syndrome in...

Objective: In the present study we have measured the concentrations of interleukin-6 (IL-6), soluble IL6 receptor (sIL-6R), tumor necrosis factor-a (TNF-a), interleukin-1b (IL-1b) and IL-1 receptor antagonist (IL-1Ra) in the serum of patients with Graves' disease (GD). By multivariate analysis, we have evaluated the effect of antithyroid treatment, thyroid function, the presence or absence of a...