نتایج جستجو برای: traf3
تعداد نتایج: 406 فیلتر نتایج به سال:
Abstract Severe COVID-19, caused by Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is characterized widespread inflammation and cytokine storm. A number of viral proteins are capable inducing inflammatory responses, one which open reading frame 3a (ORF3a). ORF3a from SARS-CoV shares 73% homology with SARS-CoV-2 was shown to stimulate NF-κB signaling inflammasome activation in a manner d...
BACKGROUND AND AIMS Whether EPA and DHA exert similar anti-inflammatory effects through modulation of gene expression in immune cells remains unclear. The aim of the study was to compare the impact of EPA and DHA supplementation on inflammatory gene expression in subjects at risk for cardiometabolic diseases. METHODS In this randomized double-blind crossover trial, 154 men and women with abdo...
TRAF3 Epigenetic Regulation Is Associated With Vascular Recurrence in Patients With Ischemic Stroke.
BACKGROUND AND PURPOSE Clopidogrel is one of the most used antiplatelet drugs in patients with cardiovascular disease. However, 16% to 50% of patients have a high on-clopidogrel platelet reactivity and an increased risk of ischemic events. The pathogenesis of high on-treatment platelet reactivity in patients with stroke is only partially explained by genetic variations. This study aims to find ...
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